Dichlorprop

Base Information

• Chemical Name: Dichlorprop
• CAS No.: 7547-66-2
• Molecular Formula: C₉H₈Cl₂O₃
• Molecular Weight: 235.067
• Mol file: 7547-66-2.mol

Synonyms:2-(2,4-dichlorophenoxy)propanoic acid; 2,4-DP; 2,4-Dichlorphenoxypropionic Acid; Dichloroprop; Dichlorprop; (2,4-dichlorophenoxy)acetic acid; (2S)-2-(2,4-dichlorophenoxy)propanoic acid; (2R)-2-(2,4-dichlorophenoxy)propanoic acid; (2S)-2-(2,4-dichlorophenoxy)propanoate; (2R)-2-(2,4-dichlorophenoxy)propanoate; 2,4-Dichlorophenoxy-alpha-Propionic acid

Chemical Property of Dichlorprop

Chemical Property:

• Vapor Pressure: 1.9E-05mmHg at 25°C
• Melting Point: 110-112℃
• Boiling Point: 348.3°C at 760 mmHg
• Flash Point: 164.5°C
• PSA: 46.53000
• LogP: 2.84530

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Hazard Codes: Xn:Harmful
• Statements: R20/21/22:; R36/37/38:
• Safety Statements: S26:; S37/39:

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dichlorprop

There total 21 articles about Dichlorprop which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(R)-(+)-ethyl-2-(2,4-dichlorophenoxy)propanoate → (R)-dichlorprop (120-36-5,7547-66-2,15165-69-2,15165-67-0)

Guidance literature:

With water; potassium hydroxide; In ethanol; at 20 ℃; for 5h;

Reference yield: 86.0%

(R)-di(naphthalen-1-yl)methyl-2-(2,4-dichlorophenoxy)propanoate → (R)-dichlorprop (120-36-5,7547-66-2,15165-69-2,15165-67-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; ethanol; at 20 ℃; for 18h; Schlenk technique;

DOI:10.1021/acs.orglett.0c00748

Reference yield: 62.0%

(R)-(+)-Methyl 2-(2,4-dichlorophenoxy)propionate (122674-96-8) → (R)-dichlorprop (120-36-5,7547-66-2,15165-69-2,15165-67-0)

Guidance literature:

With potassium carbonate; In methanol; water; for 2h; Reflux;

DOI:10.1371/journal.pone.0213552

upstream raw materials:

2-(2,4-dichlorophenoxy)propanoic acid methyl ester

sodium 2,4-dichlorophenolate

n-butyl 2-(2,4-dichlorophenoxy)propanoate

brucine

Downstream raw materials:

(1R,6S,7S)-7-<<((R)-1-(2,4-dichlorophenoxy)ethyl)carbonyl>oxy>-9-methylenebicyclo<4.3.0>nonane

(1S,6R,7R)-7-<<((R)-1-(2,4-dichlorophenoxy)ethyl)carbonyl>oxy>-9-methylenebicyclo<4.3.0>nonane

(R)-2-(2,4-Dichloro-phenoxy)-propionic acid 1-methyl-heptyl ester

(R)-2-(2,4-dichlorophenoxy)propionyl chloride

Refernces

• 1、 Nakagita, Tomoya,Matsuya, Takumi,Narukawa, Masataka,Misaka, Takumi,Kobayashi, Takuya,Ishida, Akiko,Hashimoto, Makoto,Hirokawa, Takatsugu. "Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor". . . Retrieved 2019/04/13.
• 2、 Williams, John D.,Torhan, Matthew C.,Neelagiri, Venugopal R.,Brown, Carson,Bowlin, Nicholas O.,Di, Ming,McCarthy, Courtney T.,Aiello, Daniel,Peet, Norton P.,Bowlin, Terry L.,Moir, Donald T.. "Synthesis and structure-activity relationships of novel phenoxyacetamide inhibitors of the Pseudomonas aeruginosa type III secretion system (T3SS)". . p. 1027 - 1043. Retrieved 2015/03/04.