ETHYL (1R,2R,3R,5S)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO[3.1.0]HEXANE-3-CARBOXYLATE

Base Information

Chemical Name:ETHYL (1R*,2R*,3R*,5S*)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO[3.1.0]HEXANE-3-CARBOXYLATE
CAS No.:959745-77-8
Molecular Formula:C₂₃H₂₃NO₅
Molecular Weight:393.439
Hs Code.:2932990090
Mol file:959745-77-8.mol

Synonyms:ETHYL (1R*,2R*,3R*,5S*)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO[3.1.0]HEXANE-3-CARBOXYLATE

Suppliers and Price of ETHYL (1R*,2R*,3R*,5S*)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO[3.1.0]HEXANE-3-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL(1R,2R,3R,5S)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO(3.1.0)HEXANE-3-CARBOXYLATE 95.00%
5MG
$ 496.42

Total 2 raw suppliers

Chemical Property of ETHYL (1R*,2R*,3R*,5S*)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO[3.1.0]HEXANE-3-CARBOXYLATE

Chemical Property:

Vapor Pressure:5.24E-13mmHg at 25°C
Boiling Point:570°C at 760 mmHg
Flash Point:298.6°C
PSA：77.16000
Density:1.33g/cm³
LogP:3.63500

Purity/Quality:

95% ^*data from raw suppliers

ETHYL(1R,2R,3R,5S)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO(3.1.0)HEXANE-3-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ETHYL (1R*,2R*,3R*,5S*)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO[3.1.0]HEXANE-3-CARBOXYLATE

There total 11 articles about ETHYL (1R*,2R*,3R*,5S*)-2-(9-FLUORENYLMETHOXYCARBONYLAMINO)-6-OXA-BICYCLO[3.1.0]HEXANE-3-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: (1S*,2S*)-ethyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)cyclopent-3-enecarboxylate

: 959745-77-8
(1R*,2R*,3S*,5S*)-ethyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-oxabicyclo[3.1.0]hexane-3-carboxylate

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃; for 6h; diastereoselective reaction;
DOI:10.1080/00397911.2020.1733612

Reference yield: 58.0%

: ethyl cis-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)cyclopent-3-ene-1-carboxylate

: 959745-77-8
ethyl (1RS,2RS,3RS,5SR)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-oxabicyclo[3.1.0]hexane-3-carboxylate

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃; for 6h; diastereoselective reaction;
DOI:10.1080/00397911.2020.1733612

Reference yield:

: (1S*,2S*)-ethyl 2-aminocyclopent-3-enecarboxylate trifluoroacetate

: 959745-77-8
(1R*,2R*,3S*,5S*)-ethyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-oxabicyclo[3.1.0]hexane-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 8 h / 0 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 6 h / 0 - 20 °C

With triethylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1080/00397911.2020.1733612