Ethyl 3-hydroxycyclopentanecarboxylate

Base Information

• Chemical Name: Ethyl 3-hydroxycyclopentanecarboxylate
• CAS No.: 1187933-07-8
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.197
• European Community (EC) Number: 861-561-2
• DSSTox Substance ID: DTXSID701284832
• Nikkaji Number: J2.200.683E
• Mol file: 1187933-07-8.mol

Synonyms:ethyl 3-hydroxycyclopentanecarboxylate;1187933-07-8;3-HYDROXY-CYCLOPENTANECARBOXYLIC ACID ETHYL ESTER;ethyl 3-hydroxycyclopentane-1-carboxylate;MFCD12913653;SCHEMBL358316;PEOQPQHZHDFVIL-UHFFFAOYSA-N;DTXSID701284832;ethyl3-hydroxycyclopentanecarboxylate;SB31544;AS-68057;SY237130;CS-0342515;FT-0703312;3-Hydroxycyclopentanecarboxylic acid ethyl ester;EN300-1697178;3-Hydroxycyclopentane-1-carboxylic acid ethyl ester

Chemical Property of Ethyl 3-hydroxycyclopentanecarboxylate

Chemical Property:

• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 158.094294304
• Heavy Atom Count: 11
• Complexity: 144

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1CCC(C1)O

Technology Process of Ethyl 3-hydroxycyclopentanecarboxylate

There total 2 articles about Ethyl 3-hydroxycyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl cyclopent-1-enecarboxylate (10267-94-4) → 1-amino-cyclopentanemethanol (3637-61-4) + 3-hydroxy-cyclopentanecarboxylic acid ethyl ester (1187933-07-8) + (S)-ethyl 3-hydroxycyclopent-1-ene-1-carboxylate + (R)-ethyl 3-hydroxycyclopent-1-ene-1-carboxylate

Guidance literature:

With Rhizopus oryzae CBS 112.07 whole cells; In dimethyl sulfoxide; at 25 ℃; for 120h;

DOI:10.1039/c7gc02215h

Reference yield:

1-(carboxymethoxy)cyclopentadiene (25662-28-6) → 1-amino-cyclopentanemethanol (3637-61-4) + 3-hydroxy-cyclopentanecarboxylic acid ethyl ester (1187933-07-8) + (S)-ethyl 3-hydroxycyclopent-1-ene-1-carboxylate + (R)-ethyl 3-hydroxycyclopent-1-ene-1-carboxylate

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid

2: Rhizopus oryzae CBS 112.07 whole cells / dimethyl sulfoxide / 120 h / 25 °C

With sulfuric acid; In dimethyl sulfoxide;

DOI:10.1039/c7gc02215h

Reference yield: 97.0%

3-hydroxy-cyclopentanecarboxylic acid ethyl ester (1187933-07-8) + triisopropylsilyl trifluoromethanesulfonate (80522-42-5) → 3-triisopropylsilanyloxy-cyclopentanecarboxylic acid ethyl ester

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; for 3.5h;

upstream raw materials:

1-(carboxymethoxy)cyclopentadiene

ethyl cyclopent-1-enecarboxylate

Downstream raw materials:

3-(4-chloro-2-nitro-phenoxy)-cyclopentanecarboxylic acid ethyl ester

[3-(2-amino-4-chloro-phenoxy)-cyclopentyl]-methanol

3-(2-amino-4-chloro-phenoxy)-cyclopentanecarboxylic acid ethyl ester

ethyl 3-{[5-(biphenyl-4-yl)-6-chloro-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-benzimidazol-2-yl]oxy}cyclopentanecarboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1187933-07-8 3-Hydroxy-cyclopentanecarboxylic acid ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send