N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine

Base Information

Chemical Name:N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine
CAS No.:1374507-24-0
Molecular Formula:C11H8ClF3N4
Molecular Weight:288.66
Hs Code.:
Mol file:1374507-24-0.mol

Synonyms:N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine;N1-[2-chloro-5-(trifluoromethyl)-4-pyrimidinyl]-1,3-benzenediamine;N1-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine

Suppliers and Price of N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N1-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine 97%
1g
$ 681.00

Alichem
N1-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine
1g
$ 752.96

Total 10 raw suppliers

Chemical Property of N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine

Chemical Property:

Boiling Point:439.7±45.0 °C(Predicted)
PKA:4.03±0.10(Predicted)
PSA：63.83000
Density:1.521±0.06 g/cm3(Predicted)
LogP:4.12880

Purity/Quality:

97% ^*data from raw suppliers

N1-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)benzene-1,3-diamine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine

There total 5 articles about N-[2-chloro-5-(trifluoroMethyl)-4-pyriMidinyl]-1,3-benzenediaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1374507-23-9
tert-butyl (3-((2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)aminocarboxylate

: 1374507-24-0
N′-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)phenyl-1,3-diamine

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 3932-97-6
2,4-dichloro-5-trifluoromethylpyrimidine

: 146651-75-4
tert–butyl (2–aminophenyl)carbamate

: 1374507-24-0
N′-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)phenyl-1,3-diamine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; at 20 - 30 ℃;

Reference yield:

: 68621-88-5
(3-aminophenyl)carbamic acid tert-butyl ester

: 1374507-24-0
N′-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)phenyl-1,3-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / butan-1-ol / 5 h / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 0 - 20 °C

With N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; butan-1-ol;