tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate
CAS No.:1089280-53-4
Molecular Formula:C17H26N2O3
Molecular Weight:306.405
Hs Code.:
Mol file:1089280-53-4.mol

Synonyms:tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate

Suppliers and Price of tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Piperidinecarboxylic acid 4-(4-amino-3-methoxyphenyl)-1,1-dimethylethyl ester
2.500g
$ 2476.00

Matrix Scientific
1-Piperidinecarboxylic acid 4-(4-amino-3-methoxyphenyl)-1,1-dimethylethyl ester
1g
$ 1650.00

A1 Biochem Labs
1-Piperidinecarboxylicacid,4-(4-amino-3-methoxyphenyl)-,1,1-dimethylethylester 95%
1 g
$ 1000.00

Total 12 raw suppliers

Chemical Property of tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate

Chemical Property:

Boiling Point:435.0±45.0 °C(Predicted)
PKA:4.90±0.10(Predicted)
PSA：64.79000
Density:1.113±0.06 g/cm3(Predicted)
LogP:3.91100

Purity/Quality:

97% ^*data from raw suppliers

1-Piperidinecarboxylic acid 4-(4-amino-3-methoxyphenyl)-1,1-dimethylethyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate

There total 9 articles about tert-butyl 4-(4-aMino-3-Methoxyphenyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1233145-65-7
4-(3-methoxy-4-nitro-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

: 1089280-53-4
tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 40 ℃; for 3h;

Reference yield: 90.0%

: 1246533-06-1
tert-butyl 4-(4-amino-3-methoxy-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylate

: 1089280-53-4
tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; under 1551.49 Torr;
DOI:10.1021/acs.jmedchem.6b00306

Reference yield: 81.0%

: 6627-53-8
1-chloro-3-methoxy-4-nitrobenzene

: 375853-82-0,286961-14-6
tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate

: 1089280-53-4
tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate

Guidance literature:: 1-chloro-3-methoxy-4-nitrobenzene; tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate; With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; water; at 120 ℃; for 0.833333h; microwave irradiation;

With hydrogen; In 1,4-dioxane; ethanol; water; under 760.051 Torr;