Zeoghyyvhwkdgb-uhfffaoysa-N

Base Information

• Chemical Name: Zeoghyyvhwkdgb-uhfffaoysa-N
• CAS No.: 1268520-30-4
• Molecular Formula: C13H24FNO3
• Molecular Weight: 261.33
• DSSTox Substance ID: DTXSID801130327
• Mol file: 1268520-30-4.mol

Synonyms:1268520-30-4;ZEOGHYYVHWKDGB-UHFFFAOYSA-N;DTXSID801130327;AKOS015897696;1-Piperidinecarboxylic acid, 4-(2-fluoro-3-hydroxypropyl)-, 1,1-dimethylethyl ester

Chemical Property of Zeoghyyvhwkdgb-uhfffaoysa-N

Chemical Property:

• PSA: 49.77000
• LogP: 2.29190
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 261.17402179
• Heavy Atom Count: 18
• Complexity: 270

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)N1CCC(CC1)CC(CO)F

Technology Process of Zeoghyyvhwkdgb-uhfffaoysa-N

There total 3 articles about Zeoghyyvhwkdgb-uhfffaoysa-N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H26FNO4 → C13H24FNO3 (1268520-30-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃;

DOI:10.1248/cpb.c12-00484

Reference yield:

tert butyl 4-formylpiperidine-1-carboxylate (137076-22-3) → C13H24FNO3 (1268520-30-4)

Guidance literature:

Multi-step reaction with 3 steps

1: n-butyllithium / tetrahydrofuran / 0 °C

2: 10% Pd/C; hydrogen / ethanol / 20 °C

3: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C

With lithium aluminium tetrahydride; n-butyllithium; 10% Pd/C; hydrogen; In tetrahydrofuran; ethanol; 1: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1248/cpb.c12-00484

Reference yield:

C15H24FNO4 (1417801-73-0) → C13H24FNO3 (1268520-30-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 10% Pd/C; hydrogen / ethanol / 20 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C

With lithium aluminium tetrahydride; 10% Pd/C; hydrogen; In tetrahydrofuran; ethanol;

DOI:10.1248/cpb.c12-00484

upstream raw materials:

tert butyl 4-formylpiperidine-1-carboxylate

C₁₅H₂₄FNO₄

Refernces