N-(2-fluorophenyl)-3,4-dimethoxybenzamide

Base Information

Chemical Name:N-(2-fluorophenyl)-3,4-dimethoxybenzamide
CAS No.:312734-34-2
Molecular Formula:C15H14FNO3
Molecular Weight:275.2749632
Hs Code.:
European Community (EC) Number:663-765-5
DSSTox Substance ID:DTXSID40354458
Wikidata:Q82132620
Mol file:312734-34-2.mol

Synonyms:N-(2-fluorophenyl)-3,4-dimethoxybenzamide;312734-34-2;N-(2-Fluoro-phenyl)-3,4-dimethoxy-benzamide;Cambridge id 5336730;Oprea1_620098;Oprea1_648443;F0463-0371;DTXSID40354458;STK201211;AKOS000609603;CS-0327927;AB00081251-01;AG-690/09693058;SR-01000414331;SR-01000414331-1;Z28290450

Suppliers and Price of N-(2-fluorophenyl)-3,4-dimethoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(2-Fluorophenyl)-3,4-dimethoxybenzamide 95+%
5g
$ 671.00

American Custom Chemicals Corporation
N-(2-FLUORO-PHENYL)-3,4-DIMETHOXY-BENZAMIDE 95.00%
1G
$ 479.85

Alichem
N-(2-Fluorophenyl)-3,4-dimethoxybenzamide
1g
$ 198.38

Total 8 raw suppliers

Chemical Property of N-(2-fluorophenyl)-3,4-dimethoxybenzamide

Chemical Property:

Boiling Point:333.0±42.0 °C(Predicted)
PKA:12.10±0.70(Predicted)
PSA：51.05000
Density:1.248±0.06 g/cm3(Predicted)
LogP:3.47920
Storage Temp.:2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:275.09577147
Heavy Atom Count:20
Complexity:326

Purity/Quality:

99% ^*data from raw suppliers

N-(2-Fluorophenyl)-3,4-dimethoxybenzamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C(=O)NC2=CC=CC=C2F)OC

Technology Process of N-(2-fluorophenyl)-3,4-dimethoxybenzamide

There total 1 articles about N-(2-fluorophenyl)-3,4-dimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 348-54-9
2-Fluoroaniline

: 3535-37-3
3,4-dimethoxybenzoic acid chloride

: 312734-34-2
N-(2-fluorophenyl)-3,4-dimethoxybenzamide

Guidance literature:: With triethylamine; In dichloromethane; Heating;
DOI:10.1016/j.bmc.2006.08.026

Reference yield: 76.0%

: 312734-34-2
N-(2-fluorophenyl)-3,4-dimethoxybenzamide

: 872726-67-5
N-(2-fluorophenyl)-3,4-dimethoxybenzothioamide

Guidance literature:: With Lawessons reagent; N,N,N,N,N,N-hexamethylphosphoric triamide; at 100 ℃;
DOI:10.1016/j.bmc.2006.08.026

Reference yield:

: 312734-34-2
N-(2-fluorophenyl)-3,4-dimethoxybenzamide

: 872726-54-0
4-fluoro-2-(3,4-dimethoxyphenyl)benzothiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / Lawesson's reagent; hexamethylphosphoramide / 100 °C

2: 57 percent / potassium ferricyanide(III); aq. sodium hydroxide / acetonitrile / 90 °C

With Lawessons reagent; N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; potassium hexacyanoferrate(III); In acetonitrile; 2: Jacobson cyclization;
DOI:10.1016/j.bmc.2006.08.026