6-(Boc-amino)spiro[3.3]he...

Base Information

• Chemical Name: 6-(Boc-amino)spiro[3.3]he...
• CAS No.: 1087798-38-6
• Molecular Formula: C13H21NO4
• Molecular Weight: 255.31014
• Hs Code.: 2924299090
• Mol file: 1087798-38-6.mol

Synonyms:6-(Boc-amino)spiro[3.3]he...;6-(Boc-aMino)spiro[3.3]heptane-2-carboxylic acid;2-[(2-methylpropan-2-yl)oxycarbonylamino]spiro[3.3]heptane-6-carboxylic acid

Chemical Property of 6-(Boc-amino)spiro[3.3]he...

Chemical Property:

• Boiling Point: 420.5±44.0 °C(Predicted)
• PKA: 4.69±0.40(Predicted)
• PSA: 75.63000
• Density: 1.19±0.1 g/cm3(Predicted)
• LogP: 2.54540
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

6-(Boc-amino)spiro[3.3]heptane-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-(Boc-amino)spiro[3.3]he...

There total 1 articles about 6-(Boc-amino)spiro[3.3]he... which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(+/-)-2-carbomethoxy-6-<(N-tert-butoxycarbonyl)amino>spiro<3.3>heptane (170508-14-2) → 6-[(tert-butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid (1087798-38-6)

Guidance literature:

(+/-)-2-carbomethoxy-6-<(N-tert-butoxycarbonyl)amino>spiro<3.3>heptane; With water; sodium hydroxide; In methanol; at 20 ℃; for 5h; Reflux;

With citric acid; In water; pH=3 - 3.5;

DOI:10.1021/jo101271h

Reference yield: 62.0%

6-[(tert-butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid (1087798-38-6) + benzyl alcohol (100-51-6,185532-71-2) → C20H28N2O4 (1239589-53-7)

Guidance literature:

6-[(tert-butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid; With diphenyl phosphoryl azide; triethylamine; In toluene; at 80 ℃;

benzyl alcohol; In toluene;

DOI:10.1021/jo101271h

upstream raw materials:

(+/-)-2-carbomethoxy-6-<(N-tert-butoxycarbonyl)amino>spiro<3.3>heptane

Downstream raw materials:

C₂₀H₂₈N₂O₄

Refernces