4-(Pyrimidin-2-yloxy)benzaldehyde

Base Information

• Chemical Name: 4-(Pyrimidin-2-yloxy)benzaldehyde
• CAS No.: 433920-92-4
• Molecular Formula: C₁₁H₈N₂O₂
• Molecular Weight: 200.197
• Hs Code.: 2933599090
• DSSTox Substance ID: DTXSID10377018
• Nikkaji Number: J2.767.571I
• Wikidata: Q82166028
• ChEMBL ID: CHEMBL1545931
• Mol file: 433920-92-4.mol

Synonyms:4-(Pyrimidin-2-yloxy)benzaldehyde;433920-92-4;4-pyrimidin-2-yloxybenzaldehyde;4-(2-Pyrimidinyloxy)benzenecarbaldehyde;4-(Pyrimidin-2-yloxy)-benzaldehyde;4-(2-pyrimidinyloxy)benzaldehyde;4-(2-Pyrimidinyloxy)-benzaldehyde;MLS000719163;SCHEMBL347528;CHEMBL1545931;DTXSID10377018;CGSRJSIAGKSMHU-UHFFFAOYSA-N;HMS2712L10;AR1931;MFCD03791174;AKOS000111389;SB57899;SMR000291431;BB 0238519;CS-0171521;FT-0702997;4-(pyrimidin-2-yloxy)benzaldehyde, AldrichCPR;1W-0265;A913681;J-513850;Benzeneacetic acid, .alpha.-(hydroxymethyl)-, (1.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide (1:1), (.alpha.S)-

Chemical Property of 4-(Pyrimidin-2-yloxy)benzaldehyde

Chemical Property:

• Vapor Pressure: 2.75E-06mmHg at 25°C
• Melting Point: 76-78°C
• Boiling Point: 390°C at 760 mmHg
• Flash Point: 189.6°C
• PSA: 52.08000
• Density: 1.265g/cm³
• LogP: 2.08140
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 200.058577502
• Heavy Atom Count: 15
• Complexity: 197

Purity/Quality:

97% ^*data from raw suppliers

4-(Pyrimidin-2-yloxy)benzaldehyde ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-36-43
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=C(N=C1)OC2=CC=C(C=C2)C=O

Technology Process of 4-(Pyrimidin-2-yloxy)benzaldehyde

There total 2 articles about 4-(Pyrimidin-2-yloxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluorobenzaldehyde (459-57-4) + 2-hydroxypyrimidine (557-01-7,51953-13-0) → 4-(pyrimidinyloxy)benzenecarbaldehyde (433920-92-4)

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; for 30h; Reflux;

DOI:10.2174/1386207311316030009

Reference yield:

→ 4-(pyrimidinyloxy)benzenecarbaldehyde (433920-92-4)

Guidance literature:

upstream raw materials:

4-fluorobenzaldehyde

2-hydroxypyrimidine