5-Amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid

Base Information

Chemical Name:5-Amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid
CAS No.:438243-87-9
Molecular Formula:C10H8BrN3O2
Molecular Weight:282.096
Hs Code.:2933199090
European Community (EC) Number:650-866-4
DSSTox Substance ID:DTXSID20398850
Wikidata:Q82201073
Mol file:438243-87-9.mol

Synonyms:5-Amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid;438243-87-9;5-amino-1-(4-bromophenyl)pyrazole-4-carboxylic Acid;5-AMINO-1-(4-BROMO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID;MFCD03934849;SCHEMBL594205;DTXSID20398850;LETBMJDJOXXFJY-UHFFFAOYSA-N;AKOS005255551;AS-35889;FT-0724642;EN300-148571;A924004

Suppliers and Price of 5-Amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
5-AMINO-1-(4-BROMOPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID Aldrich
250mg
$ 33.40

Crysdot
5-AMINO-1-(4-BROMOPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 97%
5g
$ 759.00

Biosynth Carbosynth
5-Amino-1-(4-bromophenyl)pyrazole-4-carboxylic acid
500 mg
$ 250.00

Biosynth Carbosynth
5-Amino-1-(4-bromophenyl)pyrazole-4-carboxylic acid
1 g
$ 400.00

Biosynth Carbosynth
5-Amino-1-(4-bromophenyl)pyrazole-4-carboxylic acid
100 mg
$ 100.00

Biosynth Carbosynth
5-Amino-1-(4-bromophenyl)pyrazole-4-carboxylic acid
50 mg
$ 65.00

Biosynth Carbosynth
5-Amino-1-(4-bromophenyl)pyrazole-4-carboxylic acid
250 mg
$ 160.00

AstaTech
5-AMINO-1-(4-BROMOPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 97%
0.25 / G
$ 146.00

AstaTech
5-AMINO-1-(4-BROMOPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 97%
1 / G
$ 366.00

AstaTech
5-AMINO-1-(4-BROMOPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID 97%
5 / G
$ 1099.00

Total 9 raw suppliers

Chemical Property of 5-Amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid

Chemical Property:

Vapor Pressure:1.17E-09mmHg at 25°C
Boiling Point:470.5°C at 760 mmHg
Flash Point:238.4°C
PSA：81.14000
Density:1.8g/cm³
LogP:2.49640
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:280.97999
Heavy Atom Count:16
Complexity:269

Purity/Quality:

97% ^*data from raw suppliers

5-AMINO-1-(4-BROMOPHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1N2C(=C(C=N2)C(=O)O)N)Br

Technology Process of 5-Amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid

There total 3 articles about 5-Amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 138907-71-8
ethyl 5-amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylate

: 438243-87-9
5-amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: ethyl 5-amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylate; With sodium hydroxide; In ethanol; for 25h; Reflux;

With hydrogenchloride; In water; at 20 ℃;
DOI:10.2174/1570178617999200728215322

Reference yield:

: 622-88-8,41931-18-4
4-bromophenylhydrazine hydrochloride

: 438243-87-9
5-amino-1-(4-bromophenyl)-1H-pyrazole-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / ethanol / 5 h / Reflux

2: sodium hydroxide / methanol; tetrahydrofuran; water / 50 °C

With sodium carbonate; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; water;
DOI:10.1021/ml5001867