Ethyl 5-methyl-1,2,3-oxadiazole-4-carboxylate

Base Information

• Chemical Name: Ethyl 5-methyl-1,2,3-oxadiazole-4-carboxylate
• CAS No.: 799257-45-7
• Molecular Formula: C6H8N2O3
• Molecular Weight: 156.141
• Hs Code.: 2934999090
• Mol file: 799257-45-7.mol

Synonyms:Ethyl 5-methyl-1,2,3-oxadiazole-4-carboxylate;5-methyl-1,2,3-Oxadiazole-4-carboxylic acid ethyl ester

Chemical Property of Ethyl 5-methyl-1,2,3-oxadiazole-4-carboxylate

Chemical Property:

• PSA: 65.22000
• LogP: 0.55470

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl 5-methyl-1,2,3-oxadiazole-4-carboxylate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 5-methyl-1,2,3-oxadiazole-4-carboxylate

There total 2 articles about Ethyl 5-methyl-1,2,3-oxadiazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-hydroxyimino-3-oxobutanoate (5408-04-8) → 5-methyl-[1,2,3]oxadiazole-4-carboxylic acid ethyl ester (799257-45-7)

Guidance literature:

With sulfuric acid; zinc; nachfolgend Versetzen mit Natriumnitrit;

Reference yield:

ethyl acetoacetate (141-97-9) → 5-methyl-[1,2,3]oxadiazole-4-carboxylic acid ethyl ester (799257-45-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite / Reaktion ueber mehrere Stufen

2: zinc dust; diluted sulfuric acid / nachfolgend Versetzen mit Natriumnitrit

With sulfuric acid; zinc; sodium nitrite;

Reference yield:

5-methyl-[1,2,3]oxadiazole-4-carboxylic acid ethyl ester (799257-45-7) → Diethyl methylmalonate (609-08-5)

Guidance literature:

upstream raw materials:

ethyl 2-hydroxyimino-3-oxobutanoate

ethyl acetoacetate

Downstream raw materials:

3-methyl-1-phenylpyrazole-4,5-dione 4-phenylhydrazone

Diethyl methylmalonate