(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one

Base Information

Chemical Name:(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one
CAS No.:156458-92-3
Molecular Formula:C18H15BrO
Molecular Weight:327.2151
Hs Code.:
DSSTox Substance ID:DTXSID20433558
Wikidata:Q82247729
Mol file:156458-92-3.mol

Synonyms:156458-92-3;(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one;(2Z)-2-(3-bromopropylidene)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-one;SCHEMBL2878604;DTXSID20433558;QVIBQLAUHHKJDM-GDNBJRDFSA-N;(Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one;2-(3-bromopropylidene)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-one

Suppliers and Price of (5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one
25 mg
$ 360.00

Biosynth Carbosynth
(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one
5 mg
$ 140.00

Biosynth Carbosynth
(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one
100 mg
$ 1529.00

Biosynth Carbosynth
(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one
50 mg
$ 841.50

Biosynth Carbosynth
(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one
25 mg
$ 463.00

Biosynth Carbosynth
(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one
10 mg
$ 254.50

AK Scientific
(2Z)-2-(3-Bromopropylidene)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaen-9-one
5mg
$ 239.00

Total 2 raw suppliers

Chemical Property of (5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one

Chemical Property:

Boiling Point:475.5±34.0 °C(Predicted)
PSA：17.07000
Density:1.440±0.06 g/cm3(Predicted)
LogP:4.64210
Solubility.:Dichloromethane
XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:326.03063
Heavy Atom Count:20
Complexity:387

Purity/Quality:

97% ^*data from raw suppliers

(5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C2=CC=CC=C2C(=CCCBr)C3=CC=CC=C3C1=O
Isomeric SMILES:C1C2=CC=CC=C2/C(=C/CCBr)/C3=CC=CC=C3C1=O

Technology Process of (5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one

There total 4 articles about (5Z)-5-(3-Bromopropylidene)-5,11-dihydro-10H-dibenzo[a,d]cyclohepten-10-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 156458-93-4
5-cyclopropyl-10-piperidin-1-yl-5H-dibenzo[a,d]cyclohepten-5-ol

: 156458-92-3
(Z)-5-γ-bromopropylidene-10,11-dihydro-10-oxo-5H-dibenzocycloheptene

: 156458-94-5
(E)-5-(γ-bromopropylidene)-10,11-dihydro-10-oxo-5H-dibenzocycloheptene

Guidance literature:: With hydrogen bromide; acetic acid; In water; for 16h; Heating / reflux;

Reference yield: 67.0%

: 156458-89-8
5-(γ-hydroxypropylidene)-(10,11-dihydro-10-oxo-5H-dibenzo)-cycloheptene

: 156458-92-3
(Z)-5-γ-bromopropylidene-10,11-dihydro-10-oxo-5H-dibenzocycloheptene

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1080/00397919408010157

Reference yield:

: 37439-92-2
10-piperidin-1-yl-dibenzo[a,d]cyclohepten-5-one

: 156458-92-3
(Z)-5-γ-bromopropylidene-10,11-dihydro-10-oxo-5H-dibenzocycloheptene

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) BuLi / 1.) THF, hexane, from -80 deg C to RT, 2.) THF, hexane, RT, 4 h

2: 100 percent / 0.1N HCl / methanol / 6 h

3: 67 percent / CBr₄, PPh₃ / CH₂Cl₂ / 2 h / 0 °C

With hydrogenchloride; n-butyllithium; carbon tetrabromide; triphenylphosphine; In methanol; dichloromethane;
DOI:10.1080/00397919408010157