Ethyl5-amino-4-cyano-1-(4-fluorophenyl)pyrazole-3-carboxylate

Base Information

• Chemical Name: Ethyl5-amino-4-cyano-1-(4-fluorophenyl)pyrazole-3-carboxylate
• CAS No.: 1001665-65-1
• Molecular Formula: C₁₃H₁₁FN₄O₂
• Molecular Weight: 274.254
• Hs Code.: 2933199090
• Mol file: 1001665-65-1.mol

Synonyms:Ethyl5-amino-4-cyano-1-(4-fluorophenyl)pyrazole-3-carboxylate;Ethyl 5-amino-4-cyano-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylate;5-Amino-4-cyano-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylic acid ethyl ester

Chemical Property of Ethyl5-amino-4-cyano-1-(4-fluorophenyl)pyrazole-3-carboxylate

Chemical Property:

• PSA: 93.93000
• LogP: 2.22318
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98% ^*data from raw suppliers

Ethyl5-amino-4-cyano-1-(4-fluorophenyl)pyrazole-3-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ethyl 5-amino-4-cyano-1-(4-fluorophenyl)pyrazole-3-carboxylate

Technology Process of Ethyl5-amino-4-cyano-1-(4-fluorophenyl)pyrazole-3-carboxylate

There total 2 articles about Ethyl5-amino-4-cyano-1-(4-fluorophenyl)pyrazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H10BrFN2O2 + malononitrile (109-77-3) → C13H11FN4O2 (1001665-65-1)

Guidance literature:

With sodium ethanolate; In ethanol; at 20 ℃; for 2h;

Reference yield:

C10H10BrFN2O2 (123345-70-0) + malononitrile (109-77-3) → C13H11FN4O2 (1001665-65-1)

Guidance literature:

With sodium ethanolate; In ethanol; at 20 ℃; for 2h;

upstream raw materials:

malononitrile

C₁₀H₁₀BrFN₂O₂

Refernces

• 1、 -. "SUBSTITUTED PYRAZOLES AS GHRELIN RECEPTOR ANTAGONISTS". Page/Page column 49. . Retrieved 2008/06/13.