(S)-Naproxen Acyl-β-D-glucuronide Benzyl Ester

Base Information

• Chemical Name: (S)-Naproxen Acyl-β-D-glucuronide Benzyl Ester
• CAS No.: 946517-36-8
• Molecular Formula: C₂₇H₂₈O₉
• Molecular Weight: 496.514
• Mol file: 946517-36-8.mol

Synonyms:(S)-Naproxen Acyl-β-D-glucuronide Benzyl Ester;1-[(αS)-6-Methoxy-α-Methyl-2-naphthaleneacetate] β-D-Glucopyranuronic Acid, PhenylMethyl Ester

Chemical Property of (S)-Naproxen Acyl-β-D-glucuronide Benzyl Ester

Chemical Property:

• Melting Point: 193-195?C
• PSA: 44.76000
• LogP: 3.61190
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility.: DMSO

Purity/Quality:

97% ^*data from raw suppliers

(S)-NaproxenAcyl-β-D-glucuronideBenzylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (S)-Naproxen Acyl-β-D-glucuronide Benzyl Ester (cas# 946517-36-8) is a compound useful in organic synthesis.

Technology Process of (S)-Naproxen Acyl-β-D-glucuronide Benzyl Ester

There total 2 articles about (S)-Naproxen Acyl-β-D-glucuronide Benzyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

(2S)-2-(6-methoxy(2-naphthyl))propanoic acid (22204-53-1) + benzyl α,β-D-glucuronate → C27H28O9 (946517-36-8) + C27H28O9 (946517-36-8)

Guidance literature:

With 4-methyl-morpholine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In acetonitrile; at 20 ℃;

DOI:10.1016/j.tet.2007.05.050

Reference yield: 67.0%

(2S)-2-(6-methoxy(2-naphthyl))propanoic acid (22204-53-1) + benzyl α,β-D-glucuronate → C27H28O9 (946517-36-8) + C27H28O9 (946517-36-8)

Guidance literature:

With 4-methyl-morpholine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In acetonitrile; at 20 ℃;

DOI:10.1016/j.tet.2007.05.050

upstream raw materials:

(2S)-2-(6-methoxy(2-naphthyl))propanoic acid

Refernces