2-(5-Fluoro-2-methyl-1H-indol-3-yl)ethanamine

Base Information

Chemical Name:2-(5-Fluoro-2-methyl-1H-indol-3-yl)ethanamine
CAS No.:1079-45-4
Molecular Formula:C₁₁H₁₃FN₂
Molecular Weight:192.236
Hs Code.:2933990090
DSSTox Substance ID:DTXSID801274484
ChEMBL ID:CHEMBL4302081
Mol file:1079-45-4.mol

Synonyms:1079-45-4;2-(5-Fluoro-2-methyl-1H-indol-3-yl)ethanamine;2-(5-Fluoro-2-methylindol-3-yl)ethylamine hydrochloride;2-(5-fluoro-2-methyl-1H-indol-3-yl)ethan-1-amine;Oprea1_277334;SCHEMBL8244089;CHEMBL4302081;DTXSID801274484;BBL022118;MFCD02656512;STK130536;AKOS005208136;5-Fluoro-2-methyl-1H-indole-3-ethanamine;BB 0249608;EU-0019560;EN300-241750;2-(5-Fluoro-2-methyl-1H-indol-3-yl)-ethylamine;2-(5-Fluoro-2-methyl-1H-indol-3-yl)-ethylamin e;2-(5-Fluoro-2-methyl-1H-indol-3-yl)ethanamine #;2-(5-fluoro-2-methyl-1H-indol-3-yl)-1-ethanamine

Suppliers and Price of 2-(5-Fluoro-2-methyl-1H-indol-3-yl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-(5-Fluoro-2-methyl-1H-indol-3-yl)ethanamine

Chemical Property:

PSA：41.81000
LogP:3.61890
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:192.10627659
Heavy Atom Count:14
Complexity:198

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2=C(N1)C=CC(=C2)F)CCN

Technology Process of 2-(5-Fluoro-2-methyl-1H-indol-3-yl)ethanamine

There total 5 articles about 2-(5-Fluoro-2-methyl-1H-indol-3-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-fluoro-2-methyl-3-[(E)-2-nitrovinyl]-1H-indole

: 1079-45-4
2-(5-fluoro-2-methyl-1H-indol-3-yl)ethanamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 80 ℃; for 2h;

Reference yield:

: 815586-68-6
5-fluoro-2-methyl-1H-indole-3-carboxaldehyde

: 1079-45-4
2-(5-fluoro-2-methyl-1H-indol-3-yl)ethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / 16 h / 110 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 80 °C

With lithium aluminium tetrahydride; ammonium acetate; In tetrahydrofuran;

Reference yield:

: 399-72-4
5-fluoro-2-methyl-1H-indole

: 1079-45-4
2-(5-fluoro-2-methyl-1H-indol-3-yl)ethanamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: trichlorophosphate / 1.17 h / -20 °C / Inert atmosphere

1.2: 1 h / -20 - 15 °C

2.1: ammonium acetate / 16 h / 110 °C

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 80 °C

With lithium aluminium tetrahydride; ammonium acetate; trichlorophosphate; In tetrahydrofuran;