2-ISOTHIOCYANATO-PENTANEDIOIC ACID DIMETHYL ESTER

Base Information

• Chemical Name: 2-ISOTHIOCYANATO-PENTANEDIOIC ACID DIMETHYL ESTER
• CAS No.: 21055-50-5
• Molecular Formula: C₈H₁₁NO₄S
• Molecular Weight: 217.246
• Hs Code.: 2930909090
• Mol file: 21055-50-5.mol

Synonyms:2-ISOTHIOCYANATO-PENTANEDIOIC ACID DIMETHYL ESTER;Dimethyl 2-isothiocyanatopentanedioate;dimethyl N-(thioxomethylene)glutamate;glutamic acid, N-carbonothioyl-, dimethyl ester;2-isothiocyanatoglutaric acid dimethyl ester;BB_NC-1626

Chemical Property of 2-ISOTHIOCYANATO-PENTANEDIOIC ACID DIMETHYL ESTER

Chemical Property:

• PSA: 97.05000
• LogP: 0.58400

Purity/Quality:

98%min ^*data from raw suppliers

dimethylN-(thioxomethylene)glutamate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ISOTHIOCYANATO-PENTANEDIOIC ACID DIMETHYL ESTER

There total 5 articles about 2-ISOTHIOCYANATO-PENTANEDIOIC ACID DIMETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

thiophosgene (463-71-8) + 2,7-diaminosuberate dihydrochloride → dimethyl 2,7-diisothiocyanatosuberate (21055-50-5)

Guidance literature:

With sodium hydrogencarbonate; In chloroform; water; for 2.5h;

DOI:10.1055/s-0031-1290825

Reference yield:

1,5-pentanedioic acid (110-94-1) → dimethyl 2,7-diisothiocyanatosuberate (21055-50-5)

Guidance literature:

Multi-step reaction with 4 steps

1: thionyl chloride; bromine

2: sodium azide / N,N-dimethyl-formamide

3: hydrogenchloride; water; triphenylphosphine

4: sodium hydrogencarbonate / chloroform; water / 2.5 h

With hydrogenchloride; thionyl chloride; sodium azide; water; bromine; sodium hydrogencarbonate; triphenylphosphine; In chloroform; water; N,N-dimethyl-formamide;

DOI:10.1055/s-0031-1290825

Reference yield:

dimethyl 2,4-dibromopentanedioate (31358-13-1,31448-67-6,149198-10-7,869-09-0) → dimethyl 2,7-diisothiocyanatosuberate (21055-50-5)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium azide / N,N-dimethyl-formamide

2: hydrogenchloride; water; triphenylphosphine

3: sodium hydrogencarbonate / chloroform; water / 2.5 h

With hydrogenchloride; sodium azide; water; sodium hydrogencarbonate; triphenylphosphine; In chloroform; water; N,N-dimethyl-formamide;

DOI:10.1055/s-0031-1290825

upstream raw materials:

1,5-pentanedioic acid

thiophosgene

dimethyl 2,4-dibromopentanedioate

Downstream raw materials:

cis-1,2-diisothiocyanatocyclohexane-1,2-dicarboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 21055-50-5 2-ISOTHIOCYANATO-PENTANEDIOIC ACID DIMETHYL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send