4-(2-((Cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide

Base Information

Chemical Name:4-(2-((Cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide
CAS No.:10080-05-4
Molecular Formula:C21H27N5O4S
Molecular Weight:325.432
Hs Code.:
European Community (EC) Number:642-316-7
UNII:160B179289
DSSTox Substance ID:DTXSID40143521
Nikkaji Number:J1.436.664D
Wikidata:Q27251758
ChEMBL ID:CHEMBL1368006
Mol file:10080-05-4.mol

Synonyms:10080-05-4;Glipizide EP Impurity H;4-(2-((Cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide;1-cyclohexyl-3-[2-(4-sulfamoylphenyl)ethyl]urea;UNII-160B179289;160B179289;4-(2-(3-Cyclohexylureido)ethyl)benzenesulfonamide;4-[2-[(Cyclohexylcarbamoyl)amino]ethyl]benzenesulphonamide;1-Cyclohexyl-3-(p-sulfamoylphenethyl)urea;4-{2-[(cyclohexylcarbamoyl)amino]ethyl}benzenesulfonamide;Glipizide Imp. H (EP);Glipizide Impurity H;CBMicro_015059;Cambridge id 6204432;Oprea1_627198;Oprea1_767535;MLS000777775;CHEMBL1368006;DTXSID40143521;HMS2744F15;4-[2-[[(Cyclohexylamino)carbonyl]amino]ethyl]benzenesulfonamide;STL357524;AKOS003660377;SMR000414096;BIM-0015111.P001;GLIPIZIDE IMPURITY H [EP IMPURITY];CS-0329913;FT-0665371;N-(4-aminosulfonylphenylethyl)-N'-cyclohexyl-urea;SR-01000230553;A1-05922;SR-01000230553-1;4-[2-(3-Cyclohexyl-ureido)-ethyl]-benzenesulfonamide;Q27251758;UREA, 1-CYCLOHEXYL-3-(P-SULFAMOYLPHENETHYL)-;Z56261634;BENZENESULFONAMIDE, 4-(2-(((CYCLOHEXYLAMINO)CARBONYL)AMINO)ETHYL)-

Suppliers and Price of 4-(2-((Cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Cyclohexyl-3-(p-sulfamoylphenethyl)urea
2.5g
$ 1320.00

A1 Biochem Labs
4-[2-[[(Cyclohexylamino)carbonyl]amino]ethyl]benzenesulfonamide 95%
500 mg
$ 600.00

Total 11 raw suppliers

Chemical Property of 4-(2-((Cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide

Chemical Property:

Melting Point:200-202℃
PSA：113.16000
LogP:3.88480
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:325.14601278
Heavy Atom Count:22
Complexity:447

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Cyclohexyl-3-(p-sulfamoylphenethyl)urea ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)NC(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N
Uses 1-Cyclohexyl-3-(p-sulfamoylphenethyl)urea is an impurity of Glipizide (G410225). 1-Cyclohexyl-3-(p-sulfamoylphenethyl)urea (Glipizide EP Impurity H) is an impurity of Glipizide (G410225).

Technology Process of 4-(2-((Cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide

There total 2 articles about 4-(2-((Cyclohexylcarbamoyl)amino)ethyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 3173-53-3
Cyclohexyl isocyanate

: 35303-76-5
4-(2-aminoethyl)benzenesulfonamide

: 10080-05-4
4-[2-(3-Cyclohexyl-ureido)-ethyl]-benzenesulfonamide

Guidance literature:: In N,N-dimethyl-formamide; at -4 - 20 ℃; for 2h; Solvent;

Reference yield:

: 10080-05-4
4-[2-(3-Cyclohexyl-ureido)-ethyl]-benzenesulfonamide

Guidance literature:: NH2-CH2-CH2-Ph-SO2-NH2, entspr. Isocyanat;

Reference yield:

: 10080-05-4
4-[2-(3-Cyclohexyl-ureido)-ethyl]-benzenesulfonamide

: 3173-53-3
Cyclohexyl isocyanate

: 10079-35-3
C₂₂H₃₄N₄O₄S

Guidance literature:: 4-[2-(3-Cyclohexyl-ureido)-ethyl]-benzenesulfonamide; With sodium hydroxide; In acetone; at 20 ℃; for 0.166667h;

Cyclohexyl isocyanate; In acetone; at 60 ℃; for 8h; Solvent; Reagent/catalyst;