Chemical Property of DBCO-Acid
Chemical Property:
- Melting Point:118-125 °C
- Boiling Point:622.0±55.0 °C(Predicted)
- PKA:4.47±0.17(Predicted)
- PSA：57.61000
- Density:1.34±0.1 g/cm3(Predicted)
- LogP:2.86280
- Storage Temp.:-20°C
- Solubility.:Soluble in dimethyl sulfoxide and dimethyl formamide.
- Purity/Quality:
-
99%, *data from raw suppliers
Dbco-acid 95% *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
-
Description
DBCO-Acid is a non-activated building block and adds minimal spacer to modified molecules. In the presence of activators such as EDC or HATU, this reagent can be used to derivatize amine-containing molecules through a stable amide bond. DBCO is commonly used for copper-free Click Chemistry reactions.
-
Uses
DBCO-Acid is a reactant in the synthesis of high-generation polyester dendrimers. Also used in the preparation of modular, plasmin sensitive, clickable poly(ethylene glycol)-heparin-laminin microsphere systems for creating growth factor gradients in peripheral nerve regeneration.
