2-(4'-aminobenzyl)imidazoline

Base Information

• Chemical Name: 2-(4'-aminobenzyl)imidazoline
• CAS No.: 13623-47-7
• Molecular Formula: C10H13 N3
• Molecular Weight: 175.23
• Hs Code.: 2933290090
• Mol file: 13623-47-7.mol

Synonyms:2-Imidazoline,2-(p-aminobenzyl)- (8CI)

Chemical Property of 2-(4'-aminobenzyl)imidazoline

Chemical Property:

• Boiling Point: 415.7°Cat760mmHg
• Flash Point: 205.2°C
• PSA: 50.41000
• Density: 1.22g/cm³
• LogP: 1.15860

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4'-aminobenzyl)imidazoline

There total 6 articles about 2-(4'-aminobenzyl)imidazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-(4-nitrobenzyl)-4,5-dihydro-1H-imidazole (112030-58-7) → 4-(4,5-dihydro-1H-imidazol-2-ylmethyl)-aniline (13623-47-7)

Guidance literature:

With hydrogen;

DOI:10.1021/jm970513p

Reference yield:

2-(4-nitro-phenyl)-acetimidic acid ethyl ester (57731-25-6) → 4-(4,5-dihydro-1H-imidazol-2-ylmethyl)-aniline (13623-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 1.) 0 deg C, 1 h, 2.) reflux, 20 min

2: 89 percent / H₂

With hydrogen; In ethanol;

DOI:10.1021/jm970513p

Reference yield:

4-Nitrophenylacetonitrile (555-21-5,34512-13-5,174848-08-9) → 4-(4,5-dihydro-1H-imidazol-2-ylmethyl)-aniline (13623-47-7)

Guidance literature:

Multi-step reaction with 3 steps

1: HCl(gas) / diethyl ether / 0 - 20 °C

2: ethanol / 1.) 0 deg C, 1 h, 2.) reflux, 20 min

3: 89 percent / H₂

With hydrogenchloride; hydrogen; In diethyl ether; ethanol;

DOI:10.1021/jm970513p

upstream raw materials:

p-aminophenylacetonitrile

ethylene diamine mono-p-toluenesulfonic acid salt

2-(4-nitrobenzyl)-4,5-dihydro-1H-imidazole

2-(4-nitro-phenyl)-acetimidic acid ethyl ester

Downstream raw materials:

4-(5-Oxy-1,2-dihydro-imidazo[1,2-a]quinoxalin-4-yl)-phenylamine

Refernces