4-Chloro-6-(4-fluorophenyl)pyrimidine

Base Information

Chemical Name:4-Chloro-6-(4-fluorophenyl)pyrimidine
CAS No.:85979-61-9
Molecular Formula:C10H6ClFN2
Molecular Weight:208.622
Hs Code.:
DSSTox Substance ID:DTXSID80344818
Nikkaji Number:J45.411G
Wikidata:Q63409363
Mol file:85979-61-9.mol

Synonyms:4-Chloro-6-(4-fluorophenyl)pyrimidine;85979-61-9;4-Chloro-6-(4-fluoro-phenyl)-pyrimidine;F1967-0496;SCHEMBL2907264;DTXSID80344818;AKOS005207987;Pyrimidine, 4-chloro-6-(4-fluorophenyl)-;EN300-238633;Q63409363;Z1267671542

Suppliers and Price of 4-Chloro-6-(4-fluorophenyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-CHLORO-6-(4-FLUOROPHENYL)PYRIMIDINE 95.00%
5MG
$ 497.39

Total 3 raw suppliers

Chemical Property of 4-Chloro-6-(4-fluorophenyl)pyrimidine

Chemical Property:

PSA：25.78000
LogP:2.93610
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:208.0203541
Heavy Atom Count:14
Complexity:183

Purity/Quality:: 4-CHLORO-6-(4-FLUOROPHENYL)PYRIMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC(=NC=N2)Cl)F

Technology Process of 4-Chloro-6-(4-fluorophenyl)pyrimidine

There total 2 articles about 4-Chloro-6-(4-fluorophenyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 85979-61-9
4-chloro-6-(4'-fluorophenyl)pyrimidine

Guidance literature:

Reference yield: 41.1%

: 1193-21-1
4,6-dichloropyrimidine

: 1765-93-1
4-fluoroboronic acid

: 85979-61-9
4-chloro-6-(4'-fluorophenyl)pyrimidine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In 1,4-dioxane; water; at 120 ℃; for 8h; Sealed tube; Inert atmosphere;

Reference yield:

: 85979-61-9
4-chloro-6-(4'-fluorophenyl)pyrimidine

: 1029719-05-8
N-[(S)-2-(4-amino-phenyl)-1-{(R)-3-[1-(3-isopropyl-phenyl)-cyclopropyl]-2-oxo-oxazolidin-5-yl}-ethyl]-acetamide

: 1029719-06-9
N-[(S)-2-{4-[6-(4-fluoro-phenyl)-pyrimidin-4-ylamino]-phenyl}-1-{(R)-3-[1-(3-isopropyl-phenyl)-cyclopropyl]-2-oxo-oxazolidin-5-yl}-ethyl]-acetamide

Guidance literature:: 4-chloro-6-(4'-fluorophenyl)pyrimidine; N-[(S)-2-(4-amino-phenyl)-1-{(R)-3-[1-(3-isopropyl-phenyl)-cyclopropyl]-2-oxo-oxazolidin-5-yl}-ethyl]-acetamide; With hydrogenchloride; In water; isopropyl alcohol; at 150 ℃; for 0.5h; Microwaves;

With sodium hydrogencarbonate; In water; acetonitrile;