N-(4-AMINOPHENYL)-N-CYCLOHEXYLAMINE

Base Information

• Chemical Name: N-(4-AMINOPHENYL)-N-CYCLOHEXYLAMINE
• CAS No.: 13663-13-3
• Molecular Formula: C12H18N2
• Molecular Weight: 190.288
• Mol file: 13663-13-3.mol

Synonyms:N-(4-AMINOPHENYL)-N-CYCLOHEXYLAMINE;1-N-CYCLOHEXYLBENZENE-1,4-DIAMINE;4-AMINO-N-CYCLOHEXYLANILINE

Chemical Property of N-(4-AMINOPHENYL)-N-CYCLOHEXYLAMINE

Chemical Property:

• PSA: 38.05000
• LogP: 3.66760

Purity/Quality:

97% ^*data from raw suppliers

1-N-cyclohexylbenzene-1,4-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-AMINOPHENYL)-N-CYCLOHEXYLAMINE

There total 7 articles about N-(4-AMINOPHENYL)-N-CYCLOHEXYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + 1,4-phenylenediamine (106-50-3) → N-Cyclohexyl-1,4-benzene diamine (13663-13-3) + N,N'-Dicyclohexyl-p-phenylenediamine (4175-38-6)

Guidance literature:

With glucose dehydrogenase; D-glucose; nicotinamide adenine dinucleotide phosphate; In aq. phosphate buffer; at 30 ℃; for 4h; pH=7; Reagent/catalyst; Enzymatic reaction;

DOI:10.1002/cctc.201701379

Reference yield:

N-cyclohexyl-4-nitroso-aniline (41657-77-6) + hexan-1-ol (111-27-3) → N-Cyclohexyl-1,4-benzene diamine (13663-13-3)

Guidance literature:

With sodium hydroxide;

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + 1,4-phenylenediamine (106-50-3) → N-Cyclohexyl-1,4-benzene diamine (13663-13-3)

Guidance literature:

With glucose dehydrogenase; D-glucose; nicotinamide adenine dinucleotide phosphate; In aq. phosphate buffer; at 30 ℃; for 4h; pH=7; Reagent/catalyst; Enzymatic reaction;

DOI:10.1002/cctc.201701379

upstream raw materials:

acetic acid-(4-amino-N-cyclohexyl-anilide)

1-bromocyclohexane

1,4-phenylenediamine

acetic acid-(N-cyclohexyl-4-nitro-anilide)

Downstream raw materials:

C₁₇H₂₆N₂O₂S

Refernces

• 1、 -. "Substituted indolines which inhibit receptor tyrosine kinases". Page column 39. . Retrieved 2008/06/13.