Dechloro ethylcloprostenolamide

Base Information

Chemical Name:Dechloro ethylcloprostenolamide
CAS No.:951319-59-8
Molecular Formula:C24H35NO5
Molecular Weight:417.546
Hs Code.:
UNII:WT448Z0Q1V
Wikidata:Q27292816
Mol file:951319-59-8.mol

Synonyms:dechloro ethylcloprostenolamide

Suppliers and Price of Dechloro ethylcloprostenolamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
16-phenoxy Prostaglandin F2α ethyl amide ≥98%
10mg
$ 591.00

Cayman Chemical
16-phenoxy Prostaglandin F2α ethyl amide ≥98%
5mg
$ 338.00

Cayman Chemical
16-phenoxy Prostaglandin F2α ethyl amide ≥98%
1mg
$ 81.00

Total 5 raw suppliers

Chemical Property of Dechloro ethylcloprostenolamide

Chemical Property:

PSA：99.02000
LogP:2.98400
XLogP3:2.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:12
Exact Mass:417.25152322
Heavy Atom Count:30
Complexity:544

Purity/Quality:

≥98% ^*data from raw suppliers

16-phenoxy Prostaglandin F2α ethyl amide ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCNC(=O)CCCC=CCC1C(CC(C1C=CC(COC2=CC=CC=C2)O)O)O
Isomeric SMILES:CCNC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](COC2=CC=CC=C2)O)O)O
Description Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. Ethyl amides of PGs serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

Technology Process of Dechloro ethylcloprostenolamide

There total 1 articles about Dechloro ethylcloprostenolamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 1201226-16-5
(5-(ethylamino)-5-oxopentyl)triphenylphosphonium bromide

: 41639-73-0
(1S,5R,6R,7R)-6-<(3R)-3-hydroxy-5-phenyl-1-pentenyl>-7-<(4-phenylbenzoyl)oxy>-2-oxabicyclo<3.3.0>octan-3-one

: 951319-59-8
bimatoprost

Guidance literature:: (1S,5R,6R,7R)-6-<(3R)-3-hydroxy-5-phenyl-1-pentenyl>-7-<(4-phenylbenzoyl)oxy>-2-oxabicyclo<3.3.0>octan-3-one; With potassium carbonate; In methanol; dichloromethane;

With diisobutylaluminium hydride; In dichloromethane; toluene;

(5-(ethylamino)-5-oxopentyl)triphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; stereoselective reaction;
DOI:10.1039/d1sc03237b