6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-A]pyridine

Base Information

Chemical Name:6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-A]pyridine
CAS No.:917252-78-9
Molecular Formula:C16H14N2O2
Molecular Weight:266.299
Hs Code.:
DSSTox Substance ID:DTXSID80582096
Wikidata:Q82473417
Mol file:917252-78-9.mol

Synonyms:917252-78-9;6-(METHOXYCARBONYL)-2-(4-METHYLPHENYL)IMIDAZO[1,2-A]PYRIDINE;methyl 2-(4-methylphenyl)imidazo[1,2-a]pyridine-6-carboxylate;Methyl 2-(p-tolyl)imidazo[1,2-a]pyridine-6-carboxylate;GGBGKTKRISZKAC-UHFFFAOYSA-N;SCHEMBL2127752;DTXSID80582096;AKOS030254603;methyl 2-(4-tolyl)-imidazo[1,2-a]pyridine-6-carboxylate

Suppliers and Price of 6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-A]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-a]pyridine
2g
$ 745.00

TRC
6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-a]pyridine
100mg
$ 80.00

Total 3 raw suppliers

Chemical Property of 6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-A]pyridine

Chemical Property:

PSA：43.60000
Density:1.19g/cm³
LogP:3.09630
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:266.105527694
Heavy Atom Count:20
Complexity:352

Purity/Quality:

98%Min ^*data from raw suppliers

6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-a]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=CN3C=C(C=CC3=N2)C(=O)OC

Technology Process of 6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-A]pyridine

There total 3 articles about 6-(Methoxycarbonyl)-2-(4-methylphenyl)imidazo[1,2-A]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 36052-24-1
methyl 6-aminonicotinoate

: 619-41-0
4-(bromoacetyl)toluene

: 917252-78-9
methyl 2-(4-methylphenyl)imidazo[1,2-a]pyridine-6-carboxylate

Guidance literature:: In ethanol; for 24h; Heating;
DOI:10.1248/cpb.54.1318

Reference yield:

: 122-00-9
para-methylacetophenone

: 917252-78-9
methyl 2-(4-methylphenyl)imidazo[1,2-a]pyridine-6-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: copper(ll) bromide / chloroform / 16 h / Reflux

2: sodium hydrogencarbonate / ethanol / 12 h / 20 - 80 °C

With sodium hydrogencarbonate; copper(ll) bromide; In ethanol; chloroform;
DOI:10.1111/cbdd.12560