N-(4-amino-2-methoxyphenyl)cyclohexanecarboxamide

Base Information

Chemical Name:N-(4-amino-2-methoxyphenyl)cyclohexanecarboxamide
CAS No.:436091-36-0
Molecular Formula:C₁₄H₂₀N₂O₂
Molecular Weight:248.325
Hs Code.:
DSSTox Substance ID:DTXSID201231652
Mol file:436091-36-0.mol

Synonyms:DTXSID201231652;AKOS000102263;436091-36-0;N-(4-amino-2-methoxyphenyl)cyclohexanecarboxamide

Suppliers and Price of N-(4-amino-2-methoxyphenyl)cyclohexanecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-amino-2-methoxyphenyl)cyclohexanecarboxamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:248.152477885
Heavy Atom Count:18
Complexity:277

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)N)NC(=O)C2CCCCC2

Technology Process of N-(4-amino-2-methoxyphenyl)cyclohexanecarboxamide

There total 4 articles about N-(4-amino-2-methoxyphenyl)cyclohexanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-(2-methoxy-4-nitrophenyl)cyclohexanecarboxamide

: 436091-36-0
cyclohexanecarboxylic acid-(4-amino-2-methoxy-anilide)

Guidance literature:: With iron; ammonium chloride; In ethanol; water; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

: 97-52-9
2-methoxy-4-nitrophenylamine

: 436091-36-0
cyclohexanecarboxylic acid-(4-amino-2-methoxy-anilide)

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 3 h / 0 °C / Reflux

2: iron; ammonium chloride / ethanol; water / 1 h / 20 °C / Inert atmosphere

With iron; ammonium chloride; triethylamine; In tetrahydrofuran; ethanol; water;

Reference yield:

: 2719-27-9
cyclohexanylcarbonyl chloride

: 436091-36-0
cyclohexanecarboxylic acid-(4-amino-2-methoxy-anilide)

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 3 h / 0 °C / Reflux

2: iron; ammonium chloride / ethanol; water / 1 h / 20 °C / Inert atmosphere

With iron; ammonium chloride; triethylamine; In tetrahydrofuran; ethanol; water;