Fentanyl-1-N-oxide

Base Information

• Chemical Name: Fentanyl-1-N-oxide
• CAS No.: 85893-37-4
• Molecular Formula: C₂₂H₂₈N₂O₂
• Molecular Weight: 352.477
• Mol file: 85893-37-4.mol

Synonyms:Fentanyl-1-N-oxide

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Fentanyl-1-N-oxide

Chemical Property:

• PKA: 4.94±0.40(Predicted)
• PSA: 49.74000
• LogP: 4.10810

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Fentanyl-1-N-oxide

There total 1 articles about Fentanyl-1-N-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.6%

N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide (437-38-7) → fentanyl N-oxide (85893-37-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; at 0 ℃; for 1h;

DOI:10.1002/rcm.4673

Reference yield:

potassium cyanide (151-50-8) + fentanyl N-oxide (85893-37-4) → N-<2-cyano-1-(2-phenethyl)-4-piperidino>-N-phenylpropane amide

Guidance literature:

With trifluoroacetic anhydride; Yield given. Multistep reaction; 1.) methylene chloride, 2.) water;

upstream raw materials:

N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide