5-Amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile

Base Information

Chemical Name:5-Amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile
CAS No.:149978-57-4
Molecular Formula:C₁₁H₁₁ClN₆
Molecular Weight:262.702
Hs Code.:
Mol file:149978-57-4.mol

Synonyms:5-Amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile;1H-Pyrazole-4-carbonitrile, 5-aMino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)- (9CI)

Suppliers and Price of 5-Amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
5-amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile
1g
$ 220.40

Total 7 raw suppliers

Chemical Property of 5-Amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile

Chemical Property:

Boiling Point:558.6±50.0 °C(Predicted)
PKA:-2.12±0.20(Predicted)
PSA：85.45000
Density:1.66
LogP:2.09358

Purity/Quality:

97% ^*data from raw suppliers

5-amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile

There total 6 articles about 5-Amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 2-hydrazino-3-chloropyrazolo[1,5-a]-4,5,6,7-tetrahydropyridine

: 368876-54-4
formylmalononitrile

: 149978-57-4
5-amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile

Guidance literature:: With acetic acid; In ethanol; at 50 ℃; for 10h; Temperature; Solvent;

Reference yield: 69.7%

: C₁₁H₁₂N₆

: 149978-57-4
5-amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile

Guidance literature:: With hydrogenchloride; dihydrogen peroxide; at 45 - 50 ℃; for 13h; Time;

Reference yield:

: 158355-42-1
{4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-2-yl}hydrazine

: 149978-57-4
5-amino-1-(3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl)-1H-pyrazole-4-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 4 h / Reflux

2: trichloromethyl chloroformate / water / 12 h / 20 - 25 °C

3: hydrogenchloride; dihydrogen peroxide / 13 h / 45 - 50 °C

With hydrogenchloride; dihydrogen peroxide; trichloromethyl chloroformate; In water; toluene;