Technology Process of 1H-Pyrrole-3-carboxylic acid, 2-(1-methylethyl)-4,5-diphenyl-
There total 6 articles about 1H-Pyrrole-3-carboxylic acid, 2-(1-methylethyl)-4,5-diphenyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
10 % Pd(OH)2/C;
In
methanol;
under 2327.23 Torr;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ammonia / tetrahydrofuran; toluene / 110 °C
2: hydrogen / 10 % Pd(OH)2/C / methanol / 2327.23 Torr
With
ammonia; hydrogen;
10 % Pd(OH)2/C;
In
tetrahydrofuran; methanol; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sodium hydride / toluene / 5 h / 80 °C
2: toluene-4-sulfonic acid / toluene / 24 h / Heating / reflux
3: acetic acid / toluene / 24 h / Heating / reflux
4: 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; triethylamine / 1,2-dimethoxyethane / 75 °C
5: ammonia / tetrahydrofuran; toluene / 110 °C
6: hydrogen / 10 % Pd(OH)2/C / methanol / 2327.23 Torr
With
ammonia; hydrogen; sodium hydride; 3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; acetic acid; triethylamine;
10 % Pd(OH)2/C; toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; toluene;
