Technology Process of Abieta-8,11,13-triene-3β,12-diol diacetate
There total 7 articles about Abieta-8,11,13-triene-3β,12-diol diacetate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid;
In
1,2-dichloro-ethane;
for 3.5h;
Heating;
DOI:10.1246/bcsj.54.581
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 94.8 percent / LiAlH4 / diethyl ether / 1.5 h / Ambient temperature
2: 67.3 percent / H2 / 5percent Pd/C / methanol / 20 h / Ambient temperature
3: 96.3 percent / pyridine / 1.5 h / 74 - 77 °C
4: 95.3 percent / AlCl3 / CH2Cl2 / a) 0-5 deg C, 30 min, b) RT, 24 h
5: 83.9 percent / m-chloroperbenzoic acid, p-toluenesulfonic acid / 1,2-dichloro-ethane / 3.5 h / Heating
With
pyridine; lithium aluminium tetrahydride; aluminium trichloride; hydrogen; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid;
palladium on activated charcoal;
In
methanol; diethyl ether; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1246/bcsj.54.581
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95.3 percent / AlCl3 / CH2Cl2 / a) 0-5 deg C, 30 min, b) RT, 24 h
2: 83.9 percent / m-chloroperbenzoic acid, p-toluenesulfonic acid / 1,2-dichloro-ethane / 3.5 h / Heating
With
aluminium trichloride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; 1,2-dichloro-ethane;
DOI:10.1246/bcsj.54.581
