2-[(1S,2S)-2-tert-butylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

Chemical Name:2-[(1S,2S)-2-tert-butylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.:749885-70-9
Molecular Formula:C₁₃H₂₅BO₂
Molecular Weight:224.151
Hs Code.:

Synonyms:2-[(1S,2S)-2-tert-butylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;Trans 1-t-Butyl-cyclopropyl-2-boronic acid pinacol ester;749885-70-9;AT20919;TRANS-2-(2-(TERT-BUTYL)CYCLOPROPYL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE

Suppliers and Price of 2-[(1S,2S)-2-tert-butylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
trans-1-t-Butyl-cyclopropyl-2-boronicAcidPinacolEster
10mg
$ 200.00

TRC
trans-1-t-Butyl-cyclopropyl-2-boronicAcidPinacolEster
2mg
$ 60.00

TRC
trans-1-t-Butyl-cyclopropyl-2-boronicAcidPinacolEster
1mg
$ 45.00

Total 6 raw suppliers

Chemical Property of 2-[(1S,2S)-2-tert-butylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Boiling Point:242.8±9.0 °C(Predicted)
PSA：18.46000
Density:0.92±0.1 g/cm3(Predicted)
LogP:3.51480
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:224.1947602
Heavy Atom Count:16
Complexity:275

Purity/Quality:

99.0% ^*data from raw suppliers

trans-1-t-Butyl-cyclopropyl-2-boronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2CC2C(C)(C)C
Isomeric SMILES:B1(OC(C(O1)(C)C)(C)C)[C@H]2C[C@@H]2C(C)(C)C

Technology Process of 2-[(1S,2S)-2-tert-butylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 3 articles about 2-[(1S,2S)-2-tert-butylcyclopropyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 157945-83-0,154820-99-2
(E)-2-(3,3-dimethylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 749885-70-9
2-(trans-2-tert-butylcyclopropyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: palladium diacetate; In diethyl ether;
DOI:10.1002/adsc.200303137

Reference yield:

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 749885-70-9
2-(trans-2-tert-butylcyclopropyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: Multi-step reaction with 2 steps

1.1: HBBr₂*SMe₂ / CH₂Cl₂ / 0 °C

1.2: aq. NaOH; aq. NH₄OH / CH₂Cl₂

1.3: 84 percent / pentane / 20 °C

2.1: 45 percent / Pd(OAc)2 / diethyl ether

With dibromoborane dimethylsulfide; palladium diacetate; In diethyl ether; dichloromethane;
DOI:10.1002/adsc.200303137

Reference yield:

: 917-92-0
3,3-Dimethylbut-1-yne

: 749885-70-9
2-(trans-2-tert-butylcyclopropyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: Multi-step reaction with 2 steps

1.1: HBBr₂*SMe₂ / CH₂Cl₂ / 0 °C

1.2: aq. NaOH; aq. NH₄OH / CH₂Cl₂

1.3: 84 percent / pentane / 20 °C

2.1: 45 percent / Pd(OAc)2 / diethyl ether

With dibromoborane dimethylsulfide; palladium diacetate; In diethyl ether; dichloromethane;
DOI:10.1002/adsc.200303137