5-(Hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one

Base Information

Chemical Name:5-(Hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one
CAS No.:637343-86-3
Molecular Formula:C5H9NO3
Molecular Weight:131.131
Hs Code.:2934999090
European Community (EC) Number:853-636-3,877-924-3
ChEMBL ID:CHEMBL4532730
DSSTox Substance ID:DTXSID70560565
Nikkaji Number:J3.150.604B
Mol file:637343-86-3.mol

Synonyms:5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one;97899-29-1;5-(Hydroxymethyl)-3-methyloxazolidin-2-one;637343-86-3;MFCD31555431;CHEMBL4532730;SCHEMBL10131303;DTXSID70560565;AKOS024194675;AT34050;Propanoicacid,6-methyl-,tetradecylester;SY261018;CS-0312339;EN300-206802;Z1509012500

Suppliers and Price of 5-(Hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R)-5-(HYDROXYMETHYL)-3-METHYLOXAZOLIDIN-2-ONE 98.00%
5MG
$ 503.92

AK Scientific
5-(Hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one
250mg
$ 985.00

Total 4 raw suppliers

Chemical Property of 5-(Hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one

Chemical Property:

PSA：49.77000
LogP:-0.63280
XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:131.058243149
Heavy Atom Count:9
Complexity:125

Purity/Quality:

97% ^*data from raw suppliers

(R)-5-(HYDROXYMETHYL)-3-METHYLOXAZOLIDIN-2-ONE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CC(OC1=O)CO

Technology Process of 5-(Hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one

There total 2 articles about 5-(Hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 105-58-8,76619-83-5
Diethyl carbonate

: (2S)-3-(methylamino)propane-1,2-diol

: 637343-86-3,1315020-11-1
(5S)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one

Guidance literature:: With potassium tert-butylate; at 100 ℃; for 14h;

Reference yield:

: 637343-84-1
(S)-3-methyl-5-(trityloxymethyl)oxazolidin-2-one

: 637343-86-3,1315020-11-1
(5S)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one

Guidance literature:: With trifluoroacetic acid;
DOI:10.1016/j.bmcl.2006.01.072

Reference yield: 91.0%

: 637343-86-3,1315020-11-1
(5S)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one

: 98-59-9
p-toluenesulfonyl chloride

: [(5S)-3-methyl-2-oxo-1,3-oxazolidin-5-yl]methyl 4-methylbenzenesulfonate

Guidance literature:: (5S)-5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-one; With trimethylamine hydrochloride; triethylamine; In dichloromethane; at 0 ℃; for 0.166667h;

p-toluenesulfonyl chloride; In dichloromethane; at 20 ℃;