4-[4-(4-Methyl-piperazin-1-yl)-piperidin-1-yl]-1-nitrobenzene

Base Information

Chemical Name:4-[4-(4-Methyl-piperazin-1-yl)-piperidin-1-yl]-1-nitrobenzene
CAS No.:959795-69-8
Molecular Formula:C16H24N4O2
Molecular Weight:304.392
Hs Code.:2933599090
Mol file:959795-69-8.mol

Synonyms:4-[4-(4-Methyl-piperazin-1-yl)-piperidin-1-yl]-1-nitrobenzene;1-methyl-4-[1-(4-nitrophenyl)-4-piperidinyl]Piperazine

Suppliers and Price of 4-[4-(4-Methyl-piperazin-1-yl)-piperidin-1-yl]-1-nitrobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-Methyl-4-(1-(4-nitrophenyl)piperidin-4-yl)piperazine 97%
25g
$ 1471.00

Crysdot
1-Methyl-4-(1-(4-nitrophenyl)piperidin-4-yl)piperazine 97%
10g
$ 815.00

Crysdot
1-Methyl-4-(1-(4-nitrophenyl)piperidin-4-yl)piperazine 97%
5g
$ 489.00

Total 3 raw suppliers

Chemical Property of 4-[4-(4-Methyl-piperazin-1-yl)-piperidin-1-yl]-1-nitrobenzene

Chemical Property:

Boiling Point:457.3±45.0 °C(Predicted)
PKA:8.14±0.42(Predicted)
PSA：55.54000
Density:1.190±0.06 g/cm3(Predicted)
LogP:2.27500

Purity/Quality:

99% ^*data from raw suppliers

1-Methyl-4-(1-(4-nitrophenyl)piperidin-4-yl)piperazine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-[4-(4-Methyl-piperazin-1-yl)-piperidin-1-yl]-1-nitrobenzene

There total 4 articles about 4-[4-(4-Methyl-piperazin-1-yl)-piperidin-1-yl]-1-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

: 109-01-3
1-methyl-piperazine

: 41979-39-9
4-piperidone hydrochloride

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 959795-69-8
1-methyl-4-[1-(4-nitrophenyl)piperidin-4-yl]piperazine

Guidance literature:: 4-piperidone hydrochloride; 4-Fluoronitrobenzene; With potassium carbonate; In N,N-dimethyl-formamide; Heating;

1-methyl-piperazine; at 20 ℃; for 0.5h;

With sodium tris(acetoxy)borohydride; at 20 ℃;
DOI:10.1248/cpb.c17-00784

Reference yield:

: 109-01-3
1-methyl-piperazine

: 23499-01-6
1-(4-nitrophenyl)piperidin-4-one

: 959795-69-8
1-methyl-4-[1-(4-nitrophenyl)piperidin-4-yl]piperazine

Guidance literature:: 1-methyl-piperazine; 1-(4-nitrophenyl)piperidin-4-one; In methanol; at 20 ℃; for 5h;

With sodium cyanoborohydride; acetic acid; In methanol; at 20 ℃; for 0.5h;