Chemical Property of 5-(1-Adamantylmethylamino)pentyl-trimethylazanium;bromide;hydrobromide
Chemical Property:
- Boiling Point:°Cat760mmHg
- Flash Point:°C
- PSA：12.03000
- Density:g/cm3
- LogP:2.02190
- Storage Temp.:Desiccate at RT
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:8
- Exact Mass:454.13812
- Heavy Atom Count:23
- Complexity:301
- Purity/Quality:
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≥98% by HPLC *data from raw suppliers
IEM 1460 *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C[N+](C)(C)CCCCCNCC12CC3CC(C1)CC(C3)C2.Br.[Br-]
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Description
IEM 1460 is an adamantine derivative that blocks both AMPA- and NMDA-type glutamate receptor (GluR) channels (IC50 = 10 μM-0.1 mM). It is selective for Ca2+-permeable GluR channels, which lack the GluR2 R subunit, and has been used to identify Ca2+-permeable glutamate receptors in the brain.
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Uses
IEM 1460 is an Adamantane derivative and open-channel blocker of AMPA currents.
