1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane

Base Information

Chemical Name:1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane
CAS No.:1336986-07-2
Molecular Formula:C12H9ClD4O
Molecular Weight:212.656
Hs Code.:
Mol file:1336986-07-2.mol

Synonyms:1-(6-Chlorophenyl)-7-oxabicyclo-heptane-d4;1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane

Suppliers and Price of 1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(6-Chlorophenyl)-7-oxabicyclo-heptane-d4
10mg
$ 165.00

American Custom Chemicals Corporation
1-(6-CHLOROPHENYL)-7-OXABICYCLO-HEPTANE-D4 95.00%
5MG
$ 495.50

Total 5 raw suppliers

Chemical Property of 1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane

Chemical Property:

PSA：12.53000
LogP:3.50810
Solubility.:Chloroform, Ethyl Acetate, Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(6-Chlorophenyl)-7-oxabicyclo-heptane-d4 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-(6-Chlorophenyl)-7-oxabicyclo-heptane-d4 is Used in the preparation of a labeled ketamine metabolites.

Technology Process of 1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane

There total 4 articles about 1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1336986-06-1
1-(2-[2H₄]-chlorophenyl)cyclohexene

: 1336986-07-2
1-(2-[2H₄]-chlorophenyl)-7-oxabicyclo[4.1.0]heptane

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 25 ℃;
DOI:10.1016/j.bmcl.2011.08.021

Reference yield:

: 1219795-51-3
o-bromochlorobenzene-d4

: 1336986-07-2
1-(2-[2H₄]-chlorophenyl)-7-oxabicyclo[4.1.0]heptane

Guidance literature:: Multi-step reaction with 3 steps

1.1: iodine; magnesium / tetrahydrofuran / 0.5 h / 10 - 15 °C

1.2: 16 h / 0 - 25 °C

2.1: toluene-4-sulfonic acid / benzene / 3 h / Reflux

3.1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 25 °C

With iodine; sodium hydrogencarbonate; toluene-4-sulfonic acid; magnesium; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; benzene;
DOI:10.1016/j.bmcl.2011.08.021

Reference yield:

: 1336986-05-0
1-(2-[2H₄]-chlorophenyl)cyclohexanol

: 1336986-07-2
1-(2-[2H₄]-chlorophenyl)-7-oxabicyclo[4.1.0]heptane

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / benzene / 3 h / Reflux

2: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 25 °C

With sodium hydrogencarbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; benzene;
DOI:10.1016/j.bmcl.2011.08.021