4-(α,β)-Hydroxy Rimantadine

Base Information

Chemical Name:4-(α,β)-Hydroxy Rimantadine
CAS No.:117821-36-0
Molecular Formula:C₁₂H₂₁NO
Molecular Weight:195.305
Hs Code.:
Mol file:117821-36-0.mol

Synonyms:4-(α,β)-Hydroxy Rimantadine ;5-(1-AMinoethyl)tricyclo[3.3.1.13,7]decan-2-ol

Suppliers and Price of 4-(α,β)-Hydroxy Rimantadine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(α,β)-HydroxyRimantadine
2.5mg
$ 550.00

Total 2 raw suppliers

Chemical Property of 4-(α,β)-Hydroxy Rimantadine

Chemical Property:

PSA：46.25000
LogP:2.22110

Purity/Quality:

97% ^*data from raw suppliers

4-(α,β)-HydroxyRimantadine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses A metabolite of Rimantadine.

Technology Process of 4-(α,β)-Hydroxy Rimantadine

There total 5 articles about 4-(α,β)-Hydroxy Rimantadine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127619-48-1
1-acetyl-4-adamantanol oxime

: 117821-36-0,133908-83-5
1-(1-aminoethyl)-4-adamantanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 16h; Heating;
DOI:10.1021/jm00169a029

Reference yield:

: 127707-58-8
1-(4-hydroxyadamantan-1-yl)ethanone

: 117821-36-0,133908-83-5
1-(1-aminoethyl)-4-adamantanol

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / hydroxylamine hydrochloride, pyridine / ethanol / 2 h / Heating

2: 24 mg / LiAlH₄ / tetrahydrofuran / 16 h / Heating

With pyridine; lithium aluminium tetrahydride; hydroxylamine hydrochloride; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00169a029

Reference yield:

: 56674-87-4
4-oxoadamantane-1-carboxylic acid

: 117821-36-0,133908-83-5
1-(1-aminoethyl)-4-adamantanol

Guidance literature:: Multi-step reaction with 4 steps

1: 43 percent / NaBH₄ / ethanol / 1.) 50 deg C, 30 min, 2.) RT, 3.5 h

3: 60 percent / hydroxylamine hydrochloride, pyridine / ethanol / 2 h / Heating

4: 24 mg / LiAlH₄ / tetrahydrofuran / 16 h / Heating

With pyridine; sodium tetrahydroborate; lithium aluminium tetrahydride; hydroxylamine hydrochloride; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00169a029