N-(3-Phenyl-1,2,4-oxadiazol-5-ylmethyl)phthalimide

Base Information

Chemical Name:N-(3-Phenyl-1,2,4-oxadiazol-5-ylmethyl)phthalimide
CAS No.:219611-74-2
Molecular Formula:C₁₇H₁₁N₃O₃
Molecular Weight:305.293
Hs Code.:
Mol file:219611-74-2.mol

Synonyms:2-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-1H-Isoindole-1,3(2H)-dione

Suppliers and Price of N-(3-Phenyl-1,2,4-oxadiazol-5-ylmethyl)phthalimide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(3-Phenyl-1,2,4-oxadiazol-5-ylmethyl)phthalimide

Chemical Property:

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Technology Process of N-(3-Phenyl-1,2,4-oxadiazol-5-ylmethyl)phthalimide

There total 8 articles about N-(3-Phenyl-1,2,4-oxadiazol-5-ylmethyl)phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1074-82-4
potassium phtalimide

: 1822-94-2
5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole

: 219611-74-2
2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)isoindoline-1,3-dione

Guidance literature:: In N,N-dimethyl-formamide; at 60 ℃; for 4h;

Reference yield:

: 4702-13-0
N-phthaloylglycine

: 219611-74-2
2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)isoindoline-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexylcarbodiimide / 1,2-dimethoxy-ethane / 30 h / 20 °C

2: 1,2-dimethoxy-ethane / 16 h / Heating

With dicyclohexyl-carbodiimide; In 1,2-dimethoxyethane;
DOI:10.1016/S0022-2860(03)00418-6

Reference yield:

: 85-44-9
phthalic anhydride

: 219611-74-2
2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)isoindoline-1,3-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / 0.5 h / microwave irradiation

2: dicyclohexylcarbodiimide / 1,2-dimethoxy-ethane / 30 h / 20 °C

3: 1,2-dimethoxy-ethane / 16 h / Heating

With dicyclohexyl-carbodiimide; In 1,2-dimethoxyethane;
DOI:10.1016/S0022-2860(03)00418-6