(4-Methoxyphenyl)sulfonylcarbamic acid 1,1-dimethylethyl ester

Base Information

• Chemical Name: (4-Methoxyphenyl)sulfonylcarbamic acid 1,1-dimethylethyl ester
• CAS No.: 55125-01-4
• Molecular Formula: C12H17NO5S
• Molecular Weight: 287.337
• Mol file: 55125-01-4.mol

Synonyms:(4-Methoxyphenyl)sulfonylcarbamic acid 1,1-dimethylethyl ester

Chemical Property of (4-Methoxyphenyl)sulfonylcarbamic acid 1,1-dimethylethyl ester

Chemical Property:

• Melting Point: 108 - 110 °C
• PSA: 90.08000
• LogP: 3.38030

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-Methoxyphenyl)sulfonylcarbamic acid 1,1-dimethylethyl ester

There total 1 articles about (4-Methoxyphenyl)sulfonylcarbamic acid 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + 4-methoxybenzene sulfonamide (1129-26-6) → N-(t-butoxycarboyl)-4-methoxyphenylsulfonamide (55125-01-4)

Guidance literature:

With dmap; In dichloromethane; at 25 ℃;

DOI:10.1021/acs.orglett.8b01466

Reference yield: 99.0%

N-(t-butoxycarboyl)-4-methoxyphenylsulfonamide (55125-01-4) + C10H8(2)H2O2 → C22H23(2)H2NO6S

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 3h;

DOI:10.1021/acs.orglett.1c03830

Reference yield: 97.0%

N-(t-butoxycarboyl)-4-methoxyphenylsulfonamide (55125-01-4) + Diphenyliodonium triflate (66003-76-7) → tert-butyl (4-methoxyphenyl)sulfonyl(phenyl)carbamate

Guidance literature:

With triethylamine; copper(l) chloride; In toluene; at 20 ℃; for 10h;

DOI:10.1016/j.tet.2015.01.032

upstream raw materials:

di-tert-butyl dicarbonate

4-methoxybenzene sulfonamide

Downstream raw materials:

C₁₇H₂₅NO₅S

Refernces

• 1、 Karmakar, Rajdip,Le, Anh,Xie, Peipei,Xia, Yuanzhi,Lee, Daesung. "Reactivity of Arynes for Arene Dearomatization". supporting information. p. 4168 - 4172. Retrieved 2018/07/29.