3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea

Base Information

Chemical Name:3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea
CAS No.:685506-42-7
Molecular Formula:C₁₇H₂₁N₃O₄S
Molecular Weight:363.437
Hs Code.:
DSSTox Substance ID:DTXSID30384608
Wikidata:Q27077890
Pharos Ligand ID:ZV7KRPTS8H5L
ChEMBL ID:CHEMBL513349
Mol file:685506-42-7.mol

Synonyms:685506-42-7;GSK 264220A;GSK264220A;GSK-264220A;3-[2-methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea;CHEMBL513349;1-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)-3-phenylurea;N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea;1-(2-methyl-5-piperidin-1-ylsulfonylfuran-3-yl)-3-phenylurea;D02NHW;MLS000850100;GTPL6697;SCHEMBL15798229;DTXSID30384608;LVOVQRPAMXCXTM-UHFFFAOYSA-N;HMS2799K10;HMS3648O15;BDBM50254290;AKOS024457788;CCG-242835;NCGC00344077-02;MS-25784;SMR000456118;HY-103372;CS-0027768;SR-01000774442;SR-01000774442-2;Q27077890;N-[2-methyl-5-(piperidinosulfonyl)-3-furyl]-N'-phenylurea

Suppliers and Price of 3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
GSK 264220A
10mg
$ 423.00

TRC
GSK264220A
100mg
$ 605.00

Tocris
GSK264220A ≥98%(HPLC)
50
$ 767.00

Tocris
GSK264220A ≥98%(HPLC)
10
$ 182.00

Cayman Chemical
GSK264220A ≥98%
5mg
$ 102.00

Cayman Chemical
GSK264220A ≥98%
1mg
$ 28.00

Cayman Chemical
GSK264220A ≥98%
10mg
$ 136.00

Cayman Chemical
GSK264220A ≥98%
25mg
$ 305.00

Axon Medchem
GSK264220A 99%
2 x 25 mg
$ 572.00

ApexBio Technology
GSK264220A
10mg
$ 266.00

Total 4 raw suppliers

Chemical Property of 3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea

Chemical Property:

PSA：100.03000
LogP:4.57130
Storage Temp.:Store at +4°C
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:363.12527733
Heavy Atom Count:25
Complexity:551

Purity/Quality:

97% ^*data from raw suppliers

GSK 264220A ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=C(O1)S(=O)(=O)N2CCCCC2)NC(=O)NC3=CC=CC=C3
Uses GSK 264220A is an endothelial lipase and lipoprotein lipase inhibitor, expected to be useful for the treatment of cardiovascular disease.

Technology Process of 3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea

There total 1 articles about 3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 306936-38-9
C₁₁H₁₅NO₅S

: 62-53-3
aniline

: 681428-74-0
C₁₇H₂₀N₂O₄S

: 685506-42-7
N-[2-methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea

Guidance literature:: C₁₁H₁₅NO₅S; With diphenyl phosphoryl azide; triethylamine; In toluene;

aniline; With triethylamine; In toluene;
DOI:10.1016/j.bmcl.2008.11.033