(S)-(FLUOROMETHYL)-BENZENEETHANAMINE HYDROCHLORIDE

Base Information

Chemical Name:(S)-(FLUOROMETHYL)-BENZENEETHANAMINE HYDROCHLORIDE
CAS No.:77210-51-6
Molecular Formula:C₉H₁₂FN*ClH
Molecular Weight:189.66
Hs Code.:
Mol file:77210-51-6.mol

Synonyms:(S)-(FLUOROMETHYL)-BENZENEETHANAMINE HYDROCHLORIDE

Suppliers and Price of (S)-(FLUOROMETHYL)-BENZENEETHANAMINE HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S)-(FLUOROMETHYL)BENZENEETHANAMINE HYDROCHLORIDE 95.00%
5MG
$ 498.63

AK Scientific
(2S)-1-Fluoro-3-phenylpropan-2-amine;hydrochloride
1g
$ 1342.00

Total 5 raw suppliers

Chemical Property of (S)-(FLUOROMETHYL)-BENZENEETHANAMINE HYDROCHLORIDE

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(S)-(FLUOROMETHYL)BENZENEETHANAMINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-(FLUOROMETHYL)-BENZENEETHANAMINE HYDROCHLORIDE

There total 4 articles about (S)-(FLUOROMETHYL)-BENZENEETHANAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: N,N-diallyl-1-fluoro-3-phenylpropan-2-amine

: 77210-51-6
(S)-1-fluoro-3-phenylpropan-2-ammonium chloride

Guidance literature:: N,N-diallyl-1-fluoro-3-phenylpropan-2-amine; With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; thiosalicilyc acid; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran; at 60 ℃; for 5h; Inert atmosphere;

With hydrogenchloride; ethyl acetate; In tetrahydrofuran; water; Inert atmosphere;
DOI:10.1021/acs.joc.5b01714

Reference yield:

: 13906-90-6
2-benzylaziridine

: 77210-51-6
(+/-)-2-amino-3-fluoro-1-phenylpropane HCl salt

Guidance literature:: With pyridine; hydrogenchloride; potassium fluoride; hydrogen fluoride; at 60 ℃; for 120h;
DOI:10.1016/S0022-1139(00)85218-5

Reference yield:

: 3182-95-4
L-Phenylalaninol

: 77210-51-6
(S)-1-fluoro-3-phenylpropan-2-ammonium chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / acetonitrile / 20 °C

2.1: trifluoromethylsulfonic anhydride / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.2: 0.02 h / 20 °C / Inert atmosphere

2.3: 2 h / 90 °C / Inert atmosphere

3.1: 1,4-di(diphenylphosphino)-butane; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; thiosalicilyc acid / tetrahydrofuran / 5 h / 60 °C / Inert atmosphere

3.2: Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifluoromethylsulfonic anhydride; thiosalicilyc acid; potassium carbonate; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1021/acs.joc.5b01714