4-(Dimethylamino)-4'-methylbenzhydrol

Base Information

• Chemical Name: 4-(Dimethylamino)-4'-methylbenzhydrol
• CAS No.: 93026-72-3
• Molecular Formula: C16H19NO
• Molecular Weight: 241.333
• Hs Code.: 2921499090
• DSSTox Substance ID: DTXSID90374363
• Mol file: 93026-72-3.mol

Synonyms:4-(Dimethylamino)-4'-methylbenzhydrol;93026-72-3;[4-(dimethylamino)phenyl]-(4-methylphenyl)methanol;DTXSID90374363;4-dimethylamino-4'-methylbenzhydrol;AKOS013209718;(4-(dimethylamino)phenyl)(p-tolyl)methanol

Chemical Property of 4-(Dimethylamino)-4'-methylbenzhydrol

Chemical Property:

• PSA: 23.47000
• LogP: 3.14270
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 241.146664230
• Heavy Atom Count: 18
• Complexity: 238

Purity/Quality:

98%min ^*data from raw suppliers

4-(DIMETHYLAMINO)-4'-METHYLBENZHYDROL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(C2=CC=C(C=C2)N(C)C)O

Technology Process of 4-(Dimethylamino)-4'-methylbenzhydrol

There total 2 articles about 4-(Dimethylamino)-4'-methylbenzhydrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-dimethylamino-benzaldehyde (100-10-7) + para-methylphenylmagnesium bromide (4294-57-9) → 4-Methyl-α-<4-dimethylamino-phenyl>-benzylalkohol (93026-72-3)

Guidance literature:

DOI:10.1021/jo01048a502

Reference yield:

→ 4-Methyl-α-<4-dimethylamino-phenyl>-benzylalkohol (93026-72-3)

Guidance literature:

p-Dimethylaminobenzaldehyd, entspr. Grignard-Verb.;

Reference yield: 87.0%

4-Methyl-α-<4-dimethylamino-phenyl>-benzylalkohol (93026-72-3) → N,N-dimethyl-4-(4-methylbenzyl)aniline (54158-98-4)

Guidance literature:

With formic acid; C₁₉H₂₇ClIrN₃O⁽¹⁺⁾*Cl^(1-); In water; at 80 ℃; for 0.416667h;

DOI:10.1021/acscatal.8b02495

upstream raw materials:

4-dimethylamino-benzaldehyde

para-methylphenylmagnesium bromide

Downstream raw materials:

N,N-dimethyl-4-(4-methylbenzyl)aniline

(4-(dimethylamino)phenyl)(p-tolyl)methanone