2-(2H-1,3-benzodioxol-5-yl)acetamide

Base Information

Chemical Name:2-(2H-1,3-benzodioxol-5-yl)acetamide
CAS No.:5661-47-2
Molecular Formula:C₉H₉NO₃
Molecular Weight:179.175
Hs Code.:
UNII:G7V5LU6LB4
Nikkaji Number:J1.135.454H

Synonyms:2-(2H-1,3-benzodioxol-5-yl)acetamide;5661-47-2;Homopiperonylamide;2-(1,3-benzodioxol-5-yl)acetamide;MDPA;3,4-methylenedioxyphenylacetamide;methylenedioxyphenylacetamide;G7V5LU6LB4;Acetamide, 2-(3,4-(methylenedioxy)phenyl)-;UNII-G7V5LU6LB4;SCHEMBL1395778;GIRXKOJKVUCAIB-UHFFFAOYSA-N;2-(1,3-dioxaindan-5-yl)acetamide;MFCD19347566;BS-42017;D86622;EN300-732981

Suppliers and Price of 2-(2H-1,3-benzodioxol-5-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-(2H-1,3-benzodioxol-5-yl)acetamide

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:179.058243149
Heavy Atom Count:13
Complexity:207

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1OC2=C(O1)C=C(C=C2)CC(=O)N

Technology Process of 2-(2H-1,3-benzodioxol-5-yl)acetamide

There total 7 articles about 2-(2H-1,3-benzodioxol-5-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 2861-28-1
1,3-benzodioxole-5-acetic acid

: 5661-47-2
(1,3-benzodioxol-5-ylmethyl)-amide

Guidance literature:: With 1H-imidazole; urea; In octane; at 120 ℃; for 24h; Reagent/catalyst;
DOI:10.1039/d0sc01317j

Reference yield: 72.0%

: 4439-02-5
3,4-methylenedioxyphenylacetonitrile

: 5661-47-2
(1,3-benzodioxol-5-ylmethyl)-amide

Guidance literature:: With (PN³P)Ni(OH); water; In tetrahydrofuran; at 100 ℃; for 72h; Time; Inert atmosphere; Schlenk technique; Sealed tube;
DOI:10.1039/c8dt03403f

Reference yield:

: 4439-02-5
3,4-methylenedioxyphenylacetonitrile

: 5661-47-2
(1,3-benzodioxol-5-ylmethyl)-amide

: 2861-28-1
1,3-benzodioxole-5-acetic acid

Guidance literature:: With potassium phosphate buffer; lyophilized Zea mays nitrilase ZmNIT₂ EC 3.5.5.1; In water; at 30 ℃; for 14h; pH=7.15; Title compound not separated from byproducts;
DOI:10.1016/j.tet.2006.04.069