1-Epivalidatol

Base Information

• Chemical Name: 1-Epivalidatol
• CAS No.: 76703-50-9
• Molecular Formula: C₇H₁₄O₄
• Molecular Weight: 162.186
• Mol file: 76703-50-9.mol

Synonyms:

Chemical Property of 1-Epivalidatol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Epivalidatol

There total 5 articles about 1-Epivalidatol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acarbose (56180-94-0,68107-33-5,106864-09-9) → (3R,4R,5S,6R)-5-[(2R,3R,4R,5S,6R)-5-((2R,3R,4S,5S,6R)-5-Amino-3,4-dihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy]-6-hydroxymethyl-tetrahydro-pyran-2,3,4-triol (92567-53-8,92567-71-0) + 1D-(1,3/2,4)-1-Hydroxymethyl-2,3,4-cyclohexantriol (76703-50-9) + dihydroacarbose (85382-75-8,85440-60-4,92621-52-8,92621-65-3) + C25H45NO18 (85382-75-8,85440-60-4,92621-52-8,92621-65-3)

Guidance literature:

With hydrogen; palladium on activated charcoal; In water; at 25 ℃; for 20h; under 750.06 Torr; Yield given. Further byproducts given. Yields of byproduct given;

DOI:10.1016/0008-6215(91)80045-O

Reference yield:

acarbose (56180-94-0,68107-33-5,106864-09-9) → 5a-carba-1,5-anhydro-L-iditol (139561-46-9) + 1D-(1,3/2,4)-1-Hydroxymethyl-2,3,4-cyclohexantriol (76703-50-9) + 1D-(1,3/2,4)-1-Methyl-2,3,4-cyclohexantriol (92621-63-1) + 1D-(1,2,3/4)-1-Hydroxymethyl-2,3,4-cyclohexantriol (92621-64-2)

Guidance literature:

With hydrogen; platinum(IV) oxide; In water; for 7h; under 3000.2 Torr; Further byproducts given; Ambient temperature;

DOI:10.1016/0008-6215(84)85333-1

Reference yield:

C13H22O4 → 1D-(1,3/2,4)-1-Hydroxymethyl-2,3,4-cyclohexantriol (76703-50-9)

Guidance literature:

With acetic acid; In tetrahydrofuran; water; for 5h; Heating;

DOI:10.1002/ejoc.201100956

upstream raw materials:

acarbose

Downstream raw materials:

1-deoxy-2,3,4,6-tetra-O-acetyl-5a-carba-D-glucopyranose