5-ethyl-6-methyl-3-[(naphtho[2,3-d][1,3]oxazol-2-ylmethyl)amino]pyridin-2(1H)-one

Base Information

Chemical Name:5-ethyl-6-methyl-3-[(naphtho[2,3-d][1,3]oxazol-2-ylmethyl)amino]pyridin-2(1H)-one
CAS No.:143707-94-2
Molecular Formula:C₂₀H₁₉N₃O₂
Molecular Weight:333.39
Hs Code.:
Mol file:143707-94-2.mol

Synonyms:Naphth[2,3-d]oxazole,2(1H)-pyridinone deriv.

Suppliers and Price of 5-ethyl-6-methyl-3-[(naphtho[2,3-d][1,3]oxazol-2-ylmethyl)amino]pyridin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-ethyl-6-methyl-3-[(naphtho[2,3-d][1,3]oxazol-2-ylmethyl)amino]pyridin-2(1H)-one

Chemical Property:

Vapor Pressure:6.08E-14mmHg at 25°C
Boiling Point:591°Cat760mmHg
Flash Point:311.2°C
Density:1.28g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-ethyl-6-methyl-3-[(naphtho[2,3-d][1,3]oxazol-2-ylmethyl)amino]pyridin-2(1H)-one

There total 3 articles about 5-ethyl-6-methyl-3-[(naphtho[2,3-d][1,3]oxazol-2-ylmethyl)amino]pyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 135397-32-9
3-amino-5-ethyl-6-methyl-pyridin-2(1H)-one

: 41014-41-9
2-(chloromethyl)naphth<2,3-d>oxazole

: 143707-94-2
5-Ethyl-6-methyl-3-[(naphtho[2,3-d]oxazol-2-ylmethyl)-amino]-1H-pyridin-2-one

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In ethanol; for 20h; Heating;
DOI:10.1021/jm00099a007

Reference yield:

: 139393-81-0
5-ethyl-6-methyl-3-nitro-2(1H)-pyridinone

: 143707-94-2
5-Ethyl-6-methyl-3-[(naphtho[2,3-d]oxazol-2-ylmethyl)-amino]-1H-pyridin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / H₂ / Pd/C / methanol; tetrahydrofuran

2: 37 percent / diisopropylethylamine / ethanol / 20 h / Heating

With hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00099a007

Reference yield:

: 143745-99-7
2-ethyl-3-oxobutanal sodium salt

: 143707-94-2
5-Ethyl-6-methyl-3-[(naphtho[2,3-d]oxazol-2-ylmethyl)-amino]-1H-pyridin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / aq. piperidinium acetate

2: 68 percent / H₂ / Pd/C / methanol; tetrahydrofuran

3: 37 percent / diisopropylethylamine / ethanol / 20 h / Heating

With hydrogen; piperdinium acetate; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00099a007