2-AMINO-3-FLUORO-4-PICOLINE

Base Information

• Chemical Name: 2-AMINO-3-FLUORO-4-PICOLINE
• CAS No.: 1003710-35-7
• Molecular Formula: C₆H₇FN₂
• Molecular Weight: 126.133
• Hs Code.: 9999999999

Synonyms:2-AMINO-3-FLUORO-4-PICOLINE;3-Fluoro-4-Methyl-pyridin-2-ylaMine;3-fluoro-4-methylpyridin-2-amine

Chemical Property of 2-AMINO-3-FLUORO-4-PICOLINE

Chemical Property:

• Boiling Point: 197.7±35.0 °C(Predicted)
• PKA: 4.52±0.47(Predicted)
• PSA: 39.64000
• Density: 1.196±0.06 g/cm3(Predicted)
• LogP: 1.04140

Purity/Quality:

98%Min ^*data from raw suppliers

2-Amino-3-fluoro-4-methylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-3-FLUORO-4-PICOLINE

There total 2 articles about 2-AMINO-3-FLUORO-4-PICOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

2-Amino-4-methylpyridine (695-34-1) → 3-fluoro-4-methylpyridin-2-amine (1003710-35-7) + 2-amino-5-fluoro-4-methylpyridine (301222-66-2)

Guidance literature:

With Selectfluor; In chloroform; water; at 15 ℃; for 24h; regioselective reaction; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.8b02003

Reference yield: 55.0%

2-Amino-4-methylpyridine (695-34-1) → 3-fluoro-4-methylpyridin-2-amine (1003710-35-7)

Guidance literature:

With Selectfluor; In chloroform; water; at 15 ℃; for 24h; regioselective reaction; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.8b02003

upstream raw materials:

2-Amino-4-methylpyridine

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