Podocarpa-8,11,13-trien-19-oic acid methyl ester

Base Information

Chemical Name:Podocarpa-8,11,13-trien-19-oic acid methyl ester
CAS No.:2651-34-5
Molecular Formula:C18H24O2
Molecular Weight:272.387
Hs Code.:
Mol file:2651-34-5.mol

Synonyms:Podocarpa-8,11,13-trien-19-oic acid methyl ester

Suppliers and Price of Podocarpa-8,11,13-trien-19-oic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of Podocarpa-8,11,13-trien-19-oic acid methyl ester

Chemical Property:

Melting Point:131-132 °C
Boiling Point:352.3±31.0 °C(Predicted)
PSA：26.30000
Density:1.051±0.06 g/cm3(Predicted)
LogP:3.86990

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Podocarpa-8,11,13-trien-19-oic acid methyl ester

There total 2 articles about Podocarpa-8,11,13-trien-19-oic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Methyl 2-[2-(2-bromophenyl)ethyl]-1-methyl-3-methylenecyclohexanecarboxylate

: 1686-43-7,2651-34-5,2726-94-5,3650-04-2,3745-36-6,15292-60-1,16957-27-0,24035-56-1,108395-86-4
(+/-)-10-epi-methyl desoxypodocarpate

: 1686-43-7,2651-34-5,2726-94-5,3650-04-2,3745-36-6,15292-60-1,16957-27-0,24035-56-1,108395-86-4
methyl 1β,4aβ-dimethyl-1,2,3,4,4a,9,10,10aα-octahydrophenanthrene-1α-carboxylate

: (1S,2S)-1-Methyl-3-methylene-2-phenethyl-cyclohexanecarboxylic acid methyl ester

Guidance literature:: With palladium diacetate; sodium formate; triphenylphosphine; In N,N-dimethyl-formamide; at 95 - 100 ℃; for 36h;

Reference yield:

: Methyl 2-[2-(2-bromophenyl)ethyl]-1-methyl-3-methylenecyclohexanecarboxylate

: 1686-43-7,2651-34-5,2726-94-5,3650-04-2,3745-36-6,15292-60-1,16957-27-0,24035-56-1,108395-86-4
(+/-)-10-epi-methyl desoxypodocarpate

: 1686-43-7,2651-34-5,2726-94-5,3650-04-2,3745-36-6,15292-60-1,16957-27-0,24035-56-1,108395-86-4
methyl 1β,4aβ-dimethyl-1,2,3,4,4a,9,10,10aα-octahydrophenanthrene-1α-carboxylate

: (1S,2S)-1-Methyl-3-methylene-2-phenethyl-cyclohexanecarboxylic acid methyl ester

Guidance literature:: With palladium diacetate; sodium formate; triphenylphosphine; In N,N-dimethyl-formamide; at 95 - 100 ℃; for 36h;

Reference yield:

: 2651-34-5
methyl 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethylphenanthrene-1-carboxylate

: 199620-14-9,13007-92-6
chromium⁽⁰⁾ hexacarbonyl

: 697302-50-4,697302-51-5,12082-08-5,697302-53-7
(benzene)tricarbonylchromium

: tricarbonyl{(8,9,11,12,13,14-η)methyl podocarpa-8,11,13-trien-19-oate}chromium(0)

: tricarbonyl{(8,9,11,12,13,14-η)methyl podocarpa-8,11,13-trien-19-oate}chromium(0)

Guidance literature:: In tetrahydrofuran; dibutyl ether; The ester and Cr(CO)6 were treated with dibutyl ether and then THF, and the soln. was refluxed (N2). The react. was monitored by thin layer chromy. (C6H12/ether, 9/1).; Filtration, evapn. of solvent; Flash chromy. and development with hexane resolved 2 bands; 1. band, C6H6Cr(CO)3, 2. band mixt. of diastereomers (90%, α/β=7/3); isopiestic crystn. at 4°C gave the α-isomer; elem.anal.;
DOI:10.1016/0022-328X(88)83005-5