Technology Process of (S)-4-(2-aMino-3-((2-aMinoethyl)aMino)propyl)phenol hydrochloride(
There total 4 articles about (S)-4-(2-aMino-3-((2-aMinoethyl)aMino)propyl)phenol hydrochloride( which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
water;
at 120 ℃;
for 24h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.08 h / 20 °C
1.2: 20 °C
2.1: sodium tetrahydroborate; methanol / tetrahydrofuran / 1 h / 20 °C
3.1: triethylamine; methanesulfonyl chloride / tetrahydrofuran / 1 h / 0 - 20 °C
3.3: 18 h / 60 °C
4.1: hydrogenchloride / water / 24 h / 120 °C
With
hydrogenchloride; methanol; sodium tetrahydroborate; potassium carbonate; methanesulfonyl chloride; triethylamine;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium tetrahydroborate; methanol / tetrahydrofuran / 1 h / 20 °C
2.1: triethylamine; methanesulfonyl chloride / tetrahydrofuran / 1 h / 0 - 20 °C
2.3: 18 h / 60 °C
3.1: hydrogenchloride / water / 24 h / 120 °C
With
hydrogenchloride; methanol; sodium tetrahydroborate; methanesulfonyl chloride; triethylamine;
In
tetrahydrofuran; water;
