(+)-madindoline A

Base Information

Chemical Name:(+)-madindoline A
CAS No.:184877-64-3
Molecular Formula:C22H27NO4
Molecular Weight:369.45
Hs Code.:
DSSTox Substance ID:DTXSID40430988
Nikkaji Number:J1.277.107J
Wikidata:Q77506506
Metabolomics Workbench ID:107273
ChEMBL ID:CHEMBL382330
Mol file:184877-64-3.mol

Synonyms:madindoline A;madindoline B

Suppliers and Price of (+)-madindoline A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (+)-madindoline A

Chemical Property:

PSA：66.84000
LogP:3.17040
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:369.19400834
Heavy Atom Count:27
Complexity:686

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC1=C(C(=O)C(C1=O)(C)CN2C3C(CCO3)(C4=CC=CC=C42)O)C
Isomeric SMILES:CCCCC1=C(C(=O)[C@@](C1=O)(C)CN2[C@@H]3[C@@](CCO3)(C4=CC=CC=C42)O)C

Technology Process of (+)-madindoline A

There total 49 articles about (+)-madindoline A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 302812-74-4
(+)-madindoline A

: 184877-64-3
(+)-madindoline A

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)00939-4

Reference yield: 52.0%

: (Z)-(3aR,8aS)-3a-(tert-butyldimethylsilyloxy)-8-(4-ethylidene-2-methoxycarbonyl-2-methyl-5-trimethylsilylmethyl-3-oxo-octanyl)-3,3a,8,8a-tetrahydro-2H-furo[2,3-b]indole

: 184877-64-3
(+)-madindoline A

Guidance literature:: With tetrabutylammonium triphenyldifluorosilicate; In N,N-dimethyl-formamide; at 70 ℃; for 1.75h;
DOI:10.1016/j.tet.2005.04.056

Reference yield: 39.0%

: 912833-58-0
(Z)-2-((3aR,8aS)-3a-Hydroxy-2,3,3a,8a-tetrahydro-furo[2,3-b]indol-8-ylmethyl)-2-methyl-3-oxo-4-trimethylsilanylmethyl-non-4-enoic acid methyl ester

: 184877-64-3
(+)-madindoline A

: (+)-madindoline B

Guidance literature:: With tris(dimethylamino)sulfonium trimethylsilyldifluoride; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;
DOI:10.1016/j.tetlet.2006.07.083