Dabigatran etexilate Impurity R

Base Information

Chemical Name:Dabigatran etexilate Impurity R
CAS No.:1610758-20-7
Molecular Formula:C34H41N7O5
Molecular Weight:627.743
Hs Code.:
Mol file:1610758-20-7.mol

Synonyms:Dabigatran etexilate Impurity R

Suppliers and Price of Dabigatran etexilate Impurity R

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
O-(2-Ethylbutyl)DabigatranEthylEster
1mg
$ 160.00

Total 14 raw suppliers

Chemical Property of Dabigatran etexilate Impurity R

Chemical Property:

Melting Point:95 - 97 °C (ethyl acetate)
PKA:9.75±0.46(Predicted)
PSA：154.03000
Density:1.24±0.1 g/cm3(Predicted)
LogP:6.23180

Purity/Quality:

NLT 98% ^*data from raw suppliers

O-(2-Ethylbutyl)DabigatranEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses O-(2-Ethylbutyl) Dabigatran Ethyl Ester is an impurity of Dabigatran (D100090) Ethyl Ester, a nonpeptide, direct thrombin inhibitor. Antithrombotic.

Technology Process of Dabigatran etexilate Impurity R

There total 6 articles about Dabigatran etexilate Impurity R which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 58906-64-2
2-ethyl-1-butyl chloroformate

: 429658-95-7
3-({2-[(4-carbamimidoylphenylamino)methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}pyridin-2-yl-amino)propionic acid ethyl ester

: 1610758-20-7
C₃₄H₄₁N₇O₅

Guidance literature:: With sodium carbonate; In water; acetone; at 10 - 25 ℃;

Reference yield:

: 58906-64-2
2-ethyl-1-butyl chloroformate

: 1610758-20-7
C₃₄H₄₁N₇O₅

Guidance literature:: With potassium carbonate; In water; acetone; toluene; at 20 ℃; for 2h;
DOI:10.1021/op500084q

Reference yield:

: 97-95-0
2-ethyl-1-butanol

: 1610758-20-7
C₃₄H₄₁N₇O₅

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate; N,N-dimethyl-formamide / toluene / 1 h / 0 °C

1.2: 5 h

2.1: potassium carbonate / water; toluene; acetone / 2 h / 20 °C

With potassium carbonate; N,N-dimethyl-formamide; In water; acetone; toluene;
DOI:10.1021/op500084q