3-(Aminomethyl)-4,6-dimethylpyridin-2-amine

Base Information

Chemical Name:3-(Aminomethyl)-4,6-dimethylpyridin-2-amine
CAS No.:96551-20-1
Molecular Formula:C8H13N3
Molecular Weight:151.21
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50542864
Wikidata:Q82419656
Mol file:96551-20-1.mol

Synonyms:3-(aminomethyl)-4,6-dimethylpyridin-2-amine;96551-20-1;SCHEMBL317613;F2113-0150;DTXSID50542864;AKOS005206729

Suppliers and Price of 3-(Aminomethyl)-4,6-dimethylpyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(AMINOMETHYL)-4,6-DIMETHYLPYRIDIN-2-AMINE 95.00%
5MG
$ 496.01

Total 3 raw suppliers

Chemical Property of 3-(Aminomethyl)-4,6-dimethylpyridin-2-amine

Chemical Property:

Melting Point:135-138 °C(Solv: benzene (71-43-2))
Boiling Point:309.3±37.0 °C(Predicted)
PKA:8.20±0.29(Predicted)
PSA：64.93000
Density:1.099±0.06 g/cm3(Predicted)
LogP:2.02080
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:151.110947427
Heavy Atom Count:11
Complexity:127

Purity/Quality:: 3-(AMINOMETHYL)-4,6-DIMETHYLPYRIDIN-2-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC(=C1CN)N)C
Uses 3-(Aminomethyl)-4,6-dimethylpyridin-2-amine is used as a reactant in the preparation of 1,3,5-triazine-2,4-dione derivatives as prokineticin 2 receptor antagonists.

Technology Process of 3-(Aminomethyl)-4,6-dimethylpyridin-2-amine

There total 3 articles about 3-(Aminomethyl)-4,6-dimethylpyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5468-34-8
2–amino–3–cyano–4,6–dimethylpyridine

: 96551-20-1
2-amino-3-aminomethyl-4,6-dimethylpyridine

Guidance literature:: With lithium aluminium tetrahydride; diethyl ether;
DOI:10.1021/ja01099a042

Reference yield:

: 769-28-8,70254-47-6
2-hydroxy-4,6-dimethyl-3-carbonitrile

: 96551-20-1
2-amino-3-aminomethyl-4,6-dimethylpyridine

Guidance literature:: Multi-step reaction with 3 steps

1: PCl₅; POCl₃

2: concentrated aqueous NH₃ / 160 °C

3: LiAlH₄; diethyl ether

With ammonium hydroxide; lithium aluminium tetrahydride; diethyl ether; phosphorus pentachloride; trichlorophosphate;
DOI:10.1021/ja01099a042

Reference yield:

: 14237-71-9
2-chloro-4,6-dimethylnicotinonitrile

: 96551-20-1
2-amino-3-aminomethyl-4,6-dimethylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: concentrated aqueous NH₃ / 160 °C

2: LiAlH₄; diethyl ether

With ammonium hydroxide; lithium aluminium tetrahydride; diethyl ether;
DOI:10.1021/ja01099a042