2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-diMethoxybenzoic Acid (Donepezil IMpurity)

Base Information

• Chemical Name: 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-diMethoxybenzoic Acid (Donepezil IMpurity)
• CAS No.: 197010-25-6
• Molecular Formula: C₂₄H₂₉NO₅
• Molecular Weight: 411.498
• Mol file: 197010-25-6.mol

Synonyms:2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-diMethoxybenzoic Acid (Donepezil IMpurity);Donepezil Open ring iMpurity;4,5-DiMethoxy-2-[2-oxo-3-[1-(phenylMethyl)-4-piperidinyl]propyl]benzoic Acid;2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoic Acid

Chemical Property of 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-diMethoxybenzoic Acid (Donepezil IMpurity)

Chemical Property:

• Melting Point: 90-93?C
• Boiling Point: 551.7±45.0 °C(Predicted)
• PKA: 4.04±0.36(Predicted)
• PSA: 76.07000
• Density: 1.181±0.06 g/cm3(Predicted)
• LogP: 3.75380
• Storage Temp.: -20?C Freezer
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99.0% Min ^*data from raw suppliers

2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoicAcid(DonepezilImpurity) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-diMethoxybenzoic Acid (Donepezil IMpurity)

There total 1 articles about 2-(3-(1-Benzylpiperidin-4-yl)-2-oxopropyl)-4,5-diMethoxybenzoic Acid (Donepezil IMpurity) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

donepezil hydrochloride (142057-77-0) → C24H29NO5 (197010-25-6)

Guidance literature:

donepezil hydrochloride; With sodium methylate; sodium hydroxide; In toluene; at 0 - 25 ℃; for 0.5h;

With oxalic acid diethyl ester; In toluene; at 20 - 25 ℃;

With dihydrogen peroxide; sodium hydroxide; In methanol; at 20 - 25 ℃; for 24h; Reagent/catalyst; Solvent; Temperature;

upstream raw materials:

donepezil hydrochloride

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