Pinaverium bromide

Base Information

Chemical Name:Pinaverium bromide
CAS No.:53251-94-8
Molecular Formula:C26H41BrNO4^.Br
Molecular Weight:591.424
Hs Code.:2934999090
European Community (EC) Number:258-450-0
DSSTox Substance ID:DTXSID2048614
Wikipedia:Pinaverium_bromide
Wikidata:Q27268790
NCI Thesaurus Code:C116775
ChEMBL ID:CHEMBL1909298
Mol file:53251-94-8.mol

Synonyms:4-(6-bromoveratryl)-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)morpholinium bromide;Dicetel;Eldicet;pinaverium;pinaverium bromide

Suppliers and Price of Pinaverium bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
PinaveriumBromide
1g
$ 1590.00

SynQuest Laboratories
Pinaverium bromide
25 g
$ 190.00

SynQuest Laboratories
Pinaverium bromide
1 g
$ 40.00

SynQuest Laboratories
Pinaverium bromide
5 g
$ 65.00

Medical Isotopes, Inc.
PinaveriumBromide
10 mg
$ 860.00

CSNpharm
PinaveriumBromide
10mg
$ 48.00

CSNpharm
PinaveriumBromide
5mg
$ 35.00

Crysdot
PinaveriumBromide 97%
100g
$ 561.00

ChemScene
Pinaveriumbromide >98.0%
50mg
$ 90.00

Chem-Impex
Pinaveriumbromide,98%(HPLC) 98%(HPLC)
5G
$ 123.20

Total 102 raw suppliers

Chemical Property of Pinaverium bromide

Chemical Property:

Appearance/Colour:white crystalline powder
Melting Point:159-164 °C
PSA：36.92000
LogP:2.25510
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:591.13818
Heavy Atom Count:33
Complexity:596

Purity/Quality:

99%, ^*data from raw suppliers

PinaveriumBromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C2CCC(C1C2)CCOCC[N+]3(CCOCC3)CC4=CC(=C(C=C4Br)OC)OC)C.[Br-]
Recent ClinicalTrials:Impact of Pinaverium Bromide on Bile Duct and Pancreatic Duct Cannulation During Endoscopic Retrograde Cholangiopancreatography
Uses Spasmolytic agent with low incidence of anticholinergic effects. Antispasmodic Spasmolytic agent with low incidence of anticholinergic effects. Antispasmodic.

Technology Process of Pinaverium bromide

There total 4 articles about Pinaverium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.1%

: 53207-00-4
1-bromo-2-(bromomethyl)-4,5-dimethoxybenzene

: 38284-47-8
4-{2-[2-(6,6-dimethyl-norpinan-2-yl)-ethoxy]-ethyl}-morpholine

: 53251-94-8
Pinaverium bromide

Guidance literature:: In butanone; Solvent; Reflux;

Reference yield:

: 1440-61-5
N-chloroacetylmorpholine

: 53251-94-8
Pinaverium bromide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride / tetrahydrofuran / 0 - 20 °C

2: sodium tetrahydroborate; boron trifluoride-tetrahydrofuran complex / tetrahydrofuran / 0 °C

3: butanone / Reflux

With sodium tetrahydroborate; boron trifluoride-tetrahydrofuran complex; sodium hydride; In tetrahydrofuran; butanone;

Reference yield:

: 128-50-7
nopol

: 53251-94-8
Pinaverium bromide

Guidance literature:: Multi-step reaction with 4 steps

1: palladium on activated charcoal; hydrogen / ethanol / 20 °C

2: sodium hydride / tetrahydrofuran / 0 - 20 °C

3: sodium tetrahydroborate; boron trifluoride-tetrahydrofuran complex / tetrahydrofuran / 0 °C

4: butanone / Reflux

With sodium tetrahydroborate; boron trifluoride-tetrahydrofuran complex; palladium on activated charcoal; hydrogen; sodium hydride; In tetrahydrofuran; ethanol; butanone;